CD94 antibody

Catalog No. ABIN969031

This Mouse Monoclonal antibody specifically detects CD94 in FACS and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CD94 antibody (ABIN969031)

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD94 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: 1H1

Product Details anti-CD94 Antibody

Purpose: CD94 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD94 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD94 antibody (ABIN969031)

Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: "Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia." in: Leukemia, Vol. 22, Issue 9, pp. 1778-81, (2008) (PubMed).

Masilamani, Narayanan, Prieto, Borrego, Coligan: "Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 6, pp. 1019-34, (2008) (PubMed).

Target Details for CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Alternative Name: CD94

Background: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Tissue specificity: Natural killer cells.

Molecular Weight: 21 kDa

Gene ID: 3824

UniProt: Q13241