Cytokeratin 18 antibody (AA 391-483)
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- Target See all Cytokeratin 18 (KRT18) Antibodies
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Binding Specificity
- AA 391-483
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cytokeratin 18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purpose
- Cytokeratin 18 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. Coli.
- Clone
- 4D11E4
- Isotype
- IgG2b
- Top Product
- Discover our top product KRT18 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma." in: Journal of molecular histology, Vol. 39, Issue 2, pp. 209-16, (2008) (PubMed).
: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
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The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma." in: Journal of molecular histology, Vol. 39, Issue 2, pp. 209-16, (2008) (PubMed).
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Alternative Name
- Cytokeratin 18 (KRT18 Products)
- Background
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Description: Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Aliases: CK18, CYK18, KRT18
- Molecular Weight
- 48kDa
- Gene ID
- 3875
- HGNC
- 3875
- UniProt
- P05783
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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