FOXP2 antibody

Catalog No. ABIN969154

This Mouse Monoclonal antibody specifically detects FOXP2 in ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for FOXP2 antibody (ABIN969154)

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP2 antibody is un-conjugated

Application: ELISA

Clone: 5C11A8

Product Details anti-FOXP2 Antibody

Purpose: FOXP2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FOXP2 antibody (ABIN969154)

Konopka, Bomar, Winden, Coppola, Jonsson, Gao, Peng, Preuss, Wohlschlegel, Geschwind: "Human-specific transcriptional regulation of CNS development genes by FOXP2." in: Nature, Vol. 462, Issue 7270, pp. 213-7, (2009) (PubMed).

Ptak, Enard, Wiebe, Hellmann, Krause, Lachmann, Pääbo: "Linkage disequilibrium extends across putative selected sites in FOXP2." in: Molecular biology and evolution, Vol. 26, Issue 10, pp. 2181-4, (2009) (PubMed).

Target Details for FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Alternative Name: FOXP2

Background: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Molecular Weight: 85 kDa

Gene ID: 93986

UniProt: O15409