GFAP antibody

Catalog No. ABIN969173

The Mouse Monoclonal anti-GFAP antibody has been validated for WB, IHC, ELISA and ICC. It is suitable to detect GFAP in samples from Human. There are 2+ publications available.

Quick Overview for GFAP antibody (ABIN969173)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GFAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 6A6

Product Details anti-GFAP Antibody

Purpose: GFAP Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human GFAP expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-GFAP antibody (ABIN969173)

Beschorner, Pantazis, Jeibmann, Boy, Meyermann, Mittelbronn, Schittenhelm: "Expression of EAAT-1 distinguishes choroid plexus tumors from normal and reactive choroid plexus epithelium." in: Acta neuropathologica, Vol. 117, Issue 6, pp. 667-75, (2009) (PubMed).

Barley, Dracheva, Byne: "Subcortical oligodendrocyte- and astrocyte-associated gene expression in subjects with schizophrenia, major depression and bipolar disorder." in: Schizophrenia research, Vol. 112, Issue 1-3, pp. 54-64, (2009) (PubMed).

Target Details for GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Alternative Name: GFAP

Background: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.Tissue specificity: Expressed in cells lacking fibronectin.ABCAM:It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves.In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.

Molecular Weight: 50 kDa

UniProt: P14136