HAND1 antibody (AA 90-190)

Catalog No. ABIN969184

This Mouse Monoclonal antibody specifically detects HAND1 in ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for HAND1 antibody (AA 90-190) (ABIN969184)

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HAND1 antibody is un-conjugated

Application: ELISA

Clone: 8E7A11

Product Details anti-HAND1 Antibody

Binding Specificity: AA 90-190

Purpose: HAND1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HAND1 antibody (ABIN969184)

Lexer, Welch, Durphy, Rieseberg: "Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species." in: Molecular ecology, Vol. 12, Issue 5, pp. 1225-35, (2003) (PubMed).

Dai, Cserjesi: "The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12604-12, (2002) (PubMed).

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1

Background: HAND1: heart and neural crest derivatives expressed 1. The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Gene ID: 9421

UniProt: O96004

Pathways: Tube Formation