HSP70 antibody

Catalog No. ABIN969201

Product Details anti-HSP70 Antibody

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose: HSP70 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HSP70 expressed in E. Coli.

Clone: 5A6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HSP70 antibody (ABIN969201)

Di Tommaso, Destro, Seok, Balladore, Terracciano, Sangiovanni, Iavarone, Colombo, Jang, Yu, Jin, Morenghi, Park, Roncalli: "The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 4, pp. 746-54, (2009) (PubMed).

Elstrand, Kleinberg, Kohn, Tropé, Davidson: "Expression and clinical role of antiapoptotic proteins of the bag, heat shock, and Bcl-2 families in effusions, primary tumors, and solid metastases in ovarian carcinoma." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 211-21, (2009) (PubMed).

Target Details for HSP70

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Alternative Name: HSP70 (HSP70 Products)

Background:

Description: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Aliases: RY, APG-2, hsp70, hsp70RY, HS24/P52, MGC131852, HSPA4

Molecular Weight: 70kDa

Gene ID: 3308

HGNC: 3308

UniProt: P34932