KLHL12 antibody

Catalog No. ABIN969244

This Mouse Monoclonal antibody specifically detects KLHL12 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for KLHL12 antibody (ABIN969244)

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLHL12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2G2

Product Details anti-KLHL12 Antibody

Purpose: KLHL12 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL12 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KLHL12 antibody (ABIN969244)

Jin, Pahuja, Wickliffe, Gorur, Baumgärtel, Schekman, Rape: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).

Target Details for KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Alternative Name: KLHL12

Background: Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

Molecular Weight: 63 kDa

Gene ID: 59349

UniProt: Q53G59