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KLHL12 antibody
KLHL12
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
2G2
unconjugated
Product Details anti-KLHL12 Antibody
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Target
See all KLHL12 Antibodies
KLHL12
(Kelch-Like 12 (Drosophila) (KLHL12))
Reactivity
All reactivities for KLHL12 antibodies
Human
Host
All hosts for KLHL12 antibodies
Mouse
Clonality
All clonalities for KLHL12 antibodies
Monoclonal
Conjugate
All conjugates for KLHL12 antibodies
This KLHL12 antibody is un-conjugated
Application
All applications for KLHL12 antibodies
Western Blotting (WB), ELISA
Purpose
KLHL12 Antibody
Purification
Ascitic fluid
Immunogen
Purified recombinant fragment of human KLHL12 expressed in E. Coli.
Clone
2G2
Isotype
IgG1
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Discover our top product KLHL12 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1/10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
References for anti-KLHL12 antibody (ABIN969244)
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Jin, Pahuja, Wickliffe, Gorur, Baumgärtel, Schekman, Rape : "Ubiquitin-dependent regulation of COPII coat size and function. " in: Nature , Vol. 482 , Issue 7386 , pp. 495-500 , (2012 ) (PubMed ).
Target Details for KLHL12
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Target
KLHL12
(Kelch-Like 12 (Drosophila) (KLHL12))
Alternative Name
KLHL12 (KLHL12 Products )
Background
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
Molecular Weight
63 kDa
Gene ID
59349
UniProt
Q53G59
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