KLHL22 antibody

Catalog No. ABIN969247

This Mouse Monoclonal antibody specifically detects KLHL22 in WB, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for KLHL22 antibody (ABIN969247)

Target: KLHL22 (Kelch-Like 22 (KLHL22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLHL22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 7B10

Product Details anti-KLHL22 Antibody

Purpose: KLHL22 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL22 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KLHL22

Target: KLHL22 (Kelch-Like 22 (KLHL22))

Alternative Name: KLHL22

Background: KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.

Molecular Weight: 72 kDa

Gene ID: 84861

UniProt: Q53GT1