×
For best experience we recommend to activate Javascript in your browser.
LSD1 antibody
KDM1A
Reactivity: Human, Mouse, Monkey
WB, ELISA, IHC
Host: Mouse
Monoclonal
1B2E5
unconjugated
Product Details anti-LSD1 Antibody
(hide)
Target
See all LSD1 (KDM1A) Antibodies
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Reactivity
All reactivities for LSD1 antibodies
Human, Mouse, Monkey
Host
All hosts for LSD1 antibodies
Mouse
Clonality
All clonalities for LSD1 antibodies
Monoclonal
Conjugate
All conjugates for LSD1 antibodies
This LSD1 antibody is un-conjugated
Application
All applications for LSD1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Purpose
LSD1/AOF2 Antibody
Purification
Ascitic fluid
Immunogen
Purified recombinant fragment of human LSD1 expressed in E. Coli.
Clone
1B2E5
Isotype
IgG1
Top Product
Discover our top product KDM1A Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
ELISA: 1/10000
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
References for anti-LSD1 antibody (ABIN969264)
(hide)
Shi, Matson, Lan, Iwase, Baba, Shi : "Regulation of LSD1 histone demethylase activity by its associated factors. " in: Molecular cell , Vol. 19 , Issue 6 , pp. 857-64 , (2005 ) (PubMed ).
Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle : "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. " in: Nature , Vol. 437 , Issue 7057 , pp. 436-9 , (2005 ) (PubMed ).
Target Details for LSD1
(hide)
Target
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Alternative Name
LSD1/AOF2 (KDM1A Products )
Background
The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Molecular Weight
93 kDa
UniProt
O60341
Pathways
Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Negative Regulation of intrinsic apoptotic Signaling , Warburg Effect
Recently viewed
(hide)
Chat with us , powered by LiveChat