LSD1 antibody
(2 references)Quick Overview for LSD1 antibody (ABIN969264)
Target
See all LSD1 (KDM1A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- LSD1/AOF2 Antibody
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Purification
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human LSD1 expressed in E. Coli.
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Isotype
- IgG1
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anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 130-380) antibody
KDM1A Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 130-380) antibodyKO Validated KDM1A Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibodyKDM1A Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 3F9D2 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 709-876) antibodyKDM1A Reactivity: Human, Mouse, Monkey WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 1H2F8 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibodyKDM1A Reactivity: Human, Monkey WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 3F9A3 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852), (C-Term) antibodyKDM1A Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB7583 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 753-851) antibodyKDM1A Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 2E7 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852) antibodyKDM1A Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 108-142) antibodyKDM1A Reactivity: Human, Mouse WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 108-142), (N-Term) antibodyKDM1A Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB7579-RB7580 unconjugated
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Application Notes
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).
: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).
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: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).
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- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
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Alternative Name
- LSD1/AOF2
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Background
- The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
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Molecular Weight
- 93 kDa
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UniProt
- O60341
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
Target
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