PBK antibody

Catalog No. ABIN969345

This anti-PBK antibody is a Mouse Monoclonal antibody detecting PBK in WB, ELISA, IHC, FACS and ICC. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for PBK antibody (ABIN969345)

Target: PBK (PDZ Binding Kinase (PBK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PBK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 2C8

Product Details anti-PBK Antibody

Purpose: PBK Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human PBK expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PBK antibody (ABIN969345)

Park, Nishidate, Nakamura, Katagiri: "Critical roles of T-LAK cell-originated protein kinase in cytokinesis." in: Cancer science, Vol. 101, Issue 2, pp. 403-11, (2010) (PubMed).

Oh, Zhu, Cho, Lee, Kang, Kim, Zykova, Bode, Dong: "T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation." in: Cancer research, Vol. 67, Issue 11, pp. 5186-94, (2007) (PubMed).

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: PBK

Background: This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Molecular Weight: 36 kDa

Gene ID: 55872

UniProt: Q96KB5