PKN2 antibody

Catalog No. ABIN969363

This anti-PKN2 antibody is a Mouse Monoclonal antibody detecting PKN2 in WB, IHC, ELISA and FACS. Suitable for Human, Mouse, Rat and Monkey. This Primary Antibody has been cited in 1 publication.

Quick Overview for PKN2 antibody (ABIN969363)

Target: PKN2 (Protein Kinase N2 (PKN2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PKN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 1D1

Product Details anti-PKN2 Antibody

Purpose: PRK2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human PRK2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PKN2 antibody (ABIN969363)

Cornelis, Qi, Zhang, Kraft, Manson, Cai, Hunter, Hu: "Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry." in: Annals of internal medicine, Vol. 150, Issue 8, pp. 541-50, (2009) (PubMed).

Target Details for PKN2

Target: PKN2 (Protein Kinase N2 (PKN2))

Alternative Name: PRK2

Background: Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.

Molecular Weight: 140 kDa

Gene ID: 5586

UniProt: Q16513

Pathways: Cell-Cell Junction Organization