SMAD3 antibody
Quick Overview for SMAD3 antibody (ABIN969402)
Target
See all SMAD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- SMAD3 Antibody
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Purification
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human SMAD3 expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression." in: The American journal of pathology, Vol. 176, Issue 3, pp. 1139-47, (2010) (PubMed).
: "Association of TGFBR2 polymorphism with risk of sudden cardiac arrest in patients with coronary artery disease." in: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 6, Issue 12, pp. 1745-50, (2009) (PubMed).
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: "Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression." in: The American journal of pathology, Vol. 176, Issue 3, pp. 1139-47, (2010) (PubMed).
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- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
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Alternative Name
- SMAD3
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Background
- SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
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Molecular Weight
- 48 kDa
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UniProt
- P84022
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Pathways
- Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
Target
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