SMN1 antibody

Catalog No. ABIN969407

The Mouse Monoclonal anti-SMN1 antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect SMN1 in samples from Human and Monkey. There is 1 publication available.

Quick Overview for SMN1 antibody (ABIN969407)

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This SMN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2F1

Product Details anti-SMN1 Antibody

Purpose: SMN1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human SMN1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SMN1 antibody (ABIN969407)

Hendrickson, Donohoe, Akmaev, Sugarman, Labrousse, Boguslavskiy, Flynn, Rohlfs, Walker, Allitto, Sears, Scholl: "Differences in SMN1 allele frequencies among ethnic groups within North America." in: Journal of medical genetics, Vol. 46, Issue 9, pp. 641-4, (2009) (PubMed).

Target Details for SMN1

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Alternative Name: SMN1

Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein.

Molecular Weight: 39 kDa

UniProt: Q16637

Pathways: Ribonucleoprotein Complex Subunit Organization