SND1 antibody (AA 361-485)

Catalog No. ABIN969411

This anti-SND1 antibody is a Mouse Monoclonal antibody detecting SND1 in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for SND1 antibody (AA 361-485) (ABIN969411)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2D7

Product Details anti-SND1 Antibody

Binding Specificity: AA 361-485

Purpose: SND1/P100 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SND1 antibody (ABIN969411)

Broadhurst, Lee, Hawkins, Wheeler: "The p100 EBNA-2 coactivator: a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle." in: Biochimica et biophysica acta, Vol. 1681, Issue 2-3, pp. 126-33, (2005) (PubMed).

Tijms, Snijder: "Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100." in: The Journal of general virology, Vol. 84, Issue Pt 9, pp. 2317-22, (2003) (PubMed).

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1/P100

Background: SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

Molecular Weight: 102 kDa

UniProt: Q7KZF4