SND1 antibody (N-Term)

Catalog No. ABIN2779724

The Rabbit Polyclonal anti-SND1 antibody (ABIN2779724) specifically detects SND1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse and Rabbit samples.

Quick Overview for SND1 antibody (N-Term) (ABIN2779724)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SND1 Antibody

Binding Specificity: N-Term

Purpose: SND1 Antibody - N-terminal region

Sequence: LPDYYLVTVM LSGIKCPTFR READGSETPE PFAAEAKFFT ESRLLQRDVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SND1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112892

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Alternative Name: SND1

Background:

Background Information: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

Gene Name: Staphylococcal nuclease and tudor domain containing 1

Alternative Symbols: p100, TDRD11, Tudor-SN

Protein Name: Staphylococcal nuclease domain-containing protein 1

Molecular Weight: 100kDa

Gene ID: 27044

NCBI Accession: NP_055205

UniProt: Q7KZF4