TUBA8 antibody

Catalog No. ABIN969446

The Mouse Monoclonal anti-TUBA8 antibody has been validated for WB, ELISA, FACS, IHC and ICC. It is suitable to detect TUBA8 in samples from Human and Rat. There are 2+ publications available.

Quick Overview for TUBA8 antibody (ABIN969446)

Target: TUBA8 (Tubulin, alpha 8 (TUBA8))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBA8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 2D6

Product Details anti-TUBA8 Antibody

Purpose: TUBA8 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human TUBA8 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-TUBA8 antibody (ABIN969446)

Abdollahi, Morrison, Sirey, Molnar, Hayward, Carr, Springell, Woods, Ahmed, Hattingh, Corry, Pilz, Stoodley, Crow, Taylor, Bonthron, Sheridan: "Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia." in: American journal of human genetics, Vol. 85, Issue 5, pp. 737-44, (2009) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for TUBA8

Target: TUBA8 (Tubulin, alpha 8 (TUBA8))

Alternative Name: TUBA8

Background: This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. 

Molecular Weight: 50 kDa

UniProt: Q9NY65

Pathways: Microtubule Dynamics