SNCG antibody

Catalog No. ABIN969490

This Mouse Monoclonal antibody specifically detects SNCG in IHC and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for SNCG antibody (ABIN969490)

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNCG antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 1H10D2

Product Details anti-SNCG Antibody

Purpose: SNCG (breast cancer-specific protein 1) Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of SNCG expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SNCG antibody (ABIN969490)

Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

Brown, Lasek: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." in: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).

Target Details for SNCG

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Alternative Name: SNCG (breast cancer-specific protein 1)

Background: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Gene ID: 6623

UniProt: O76070