COTL1 antibody

Catalog No. ABIN969509

Product Details anti-COTL1 Antibody

Target: COTL1 (Coactosin-Like Protein)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This COTL1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purpose: COTL1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human COTL1 expressed in E. Coli.

Clone: 5C8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-COTL1 antibody (ABIN969509)

Jin, Shim, Kim, Chae, Chung: "Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).

Target Details for COTL1

Target: COTL1 (Coactosin-Like Protein)

Alternative Name: COTL1 (COTL1 Products)

Background: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

Molecular Weight: 16 kDa

UniProt: Q14019