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anti-Mouse (Murine) Caspase 7 Antibodies:
anti-Rat (Rattus) Caspase 7 Antibodies:
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Human Monoclonal Caspase 7 Primary Antibody for SimWes, WB - ABIN153012
Fearnhead, Rodriguez, Govek, Guo, Kobayashi, Hannon, Lazebnik: Oncogene-dependent apoptosis is mediated by caspase-9. in Proceedings of the National Academy of Sciences of the United States of America 1998
Show all 4 Pubmed References
Gerbil Polyclonal Caspase 7 Primary Antibody for IHC, IHC (fro) - ABIN4288137
Lubet, Scheiman, Bode, White, Minasian, Juliana, Boring, Steele, Grubbs: Prevention of chemically induced urinary bladder cancers by naproxen: protocols to reduce gastric toxicity in humans do not alter preventive efficacy. in Cancer prevention research (Philadelphia, Pa.) 2015
Show all 2 Pubmed References
Monoclonal Caspase 7 Primary Antibody for WB - ABIN534082
Kirsch, Doseff, Chau, Lim, de Souza-Pinto, Hansford, Kastan, Lazebnik, Hardwick: Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. in The Journal of biological chemistry 1999
Show all 3 Pubmed References
Human Monoclonal Caspase 7 Primary Antibody for IHC (p), WB - ABIN252490
Jin, Suh, Kim, Yeom, Lee, Bae: IER3 is a crucial mediator of TAp73β-induced apoptosis in cervical cancer and confers etoposide sensitivity. in Scientific reports 2015
Human Polyclonal Caspase 7 Primary Antibody for ELISA, IF - ABIN4288140
Campo, Avenoso, Campo, Nastasi, Traina, DAscola, Calatroni: Chondroitin-4-sulphate reduced oxidative injury in caerulein-induced pancreatitis in mice: the involvement of NF-kappaB translocation and apoptosis activation. in Experimental biology and medicine (Maywood, N.J.) 2008
caspase-1 (show CASP1 Antibodies) regulates dopaminergic neuronal death in the pathogenesis of Parkinson's disease in mice via caspase-7/PARP1 (show PARP1 Antibodies)/AIF (show AIFM1 Antibodies) pathway.
caspase-1 (show CASP1 Antibodies) activation is an upstream event of apoptotic caspase-7 induction in renal tubulointerstitial fibrosis
Cepharanthine treatment reduced mitochondrial membrane potential and upregulated the level of cleaved caspases, including caspase-9 (show CASP9 Antibodies) and caspase-3 (show CASP3 Antibodies)/7, in a dose-dependent fashion.
Caspase 7 has a nonapoptic function that participates in normal spermatogenesis, but also displays apoptotic function in spermatogenic dysfunction.
Our study shows for the first time activated caspase-7 in hair follicles and mast cells and indicates its non-apoptotic roles in the skin.
The results reveal that executioner caspases can modulate heart's cellularity and maturation during development, contributing novel information about caspase (show CASP3 Antibodies) biology and heart development.
Optic nerve crush activated caspase-7 in retinal ganglion cells followed by cell death. Knockout of caspase-7 partially and significantly protected against ON injury-induced RGC loss.
Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 (show CASP3 Antibodies) and -7-dependent.
genetic loss of caspase-7 promotes solar-simulated light-induced skin carcinogenesis by blocking caspase-7-mediated cleavage of keratin-17 (show KRT17 Antibodies).
Interleukin-1beta enhances FasL (show FASL Antibodies)-induced caspase-3 (show CASP3 Antibodies)/-7 activity without increasing apoptosis in primary mouse hepatocytes
overexpressed miR (show MLXIP Antibodies)-337-3p and miR-17-5p/miR (show MLXIP Antibodies)-132-3p/-212-3p can regulate executioner caspases-3 and -7, respectively.
Everolimus also induced higher levels of caspase-3 (show CASP3 Antibodies)/-7 activation in GR over GS cells, and everolimus-mediated mTOR (show FRAP1 Antibodies) inhibition lead to G2 arrest in GR cells but G1 arrest in GS cells.
CASP8 (show CASP8 Antibodies): rs1045494 (C > T), PIK3R1: rs3756668 (A > G) and CASP7: rs4353229 (T > C), were associated with longer overall survival in limited disease-small cell lung cancer patients after chemoradiotherapy
Results show that caspase-7 is phosphorylated by PAK2 (show PAK2 Antibodies) at S239 which inhibits its activity by two divergent mechanisms prior to and following caspase (show CASP3 Antibodies) activation: initial phosphorylation allosterically slows activation by upstream initiator caspases by impeding cleavage at the intersubunit linker and a second phosphorylation site directly blocks substrate binding.
Caspase-7 regions involved in the interaction with Hsp90 co-chaperone p23 (show PTGES3 Antibodies) and substrate recognition.
Study provides evidence that a loss-of-function variant rs10553596 in CASP7 associates with significantly reduced Alzheimer's disease incidence in elder populations.
Thymoquinone-triggered apoptosis was substantiated by up-regulation of the executioner caspase-3 (show CASP3 Antibodies) and caspase-7, as well as cleavage of the death substrate poly(ADP-ribose)polymerase (show PARP1 Antibodies).
Casp3 (show CASP3 Antibodies)/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis.
Low expression of CASP7 is associated with non-small cell lung cancer.
this report suggests a novel finding that cellular signaling caspase 3 (show CASP3 Antibodies)/7-PKCdelta (show PKCd Antibodies)-Akt (show AKT1 Antibodies)/p38 MAPK (show MAPK14 Antibodies) is crucial to the repopulation in Panc1 cells after radiotherapy.
mRNA expression of Bax (show BAX Antibodies), Bcl-2 (show BCL2 Antibodies), caspase-3 (show CASP3 Antibodies) and-7 cannot be used as a reliable apoptosis detection method.
the capacity for blastocysts to undergo further development is related to degree of group II caspase (show CASP3 Antibodies) activity
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, caspase 7
, apoptotic protease Mch-3
, cysteine protease LICE2
, ICE-like apoptotic protease 3
, apoptotic protease MCH-3
, caspase 7, apoptosis-related cysteine protease
, Apoptotic protease Mch-3
, SREBP cleavage activity 2