Browse our anti-CD11b (ITGAM) Antibodies

Full name:: anti-Integrin alpha M Antibodies (ITGAM)

On www.antibodies-online.com are 1131 Integrin alpha M (ITGAM) Antibodies from 35 different suppliers available. Additionally we are shipping CD11b Kits (26) and CD11b Proteins (21) and many more products for this protein. A total of 1184 CD11b products are currently listed.

Synonyms:: C3bi, CD11B, CD11b/CD18, CR3, CR3A, F730045J24Rik, Ly-40, MAC-1, Mac-1a, MAC1, MAC1A, MO1A, SLEB6

list all antibodies	Gene Name	GeneID	UniProt
	ITGAM	16409
	ITGAM	25021
	ITGAM	3684	P11215
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Most Popular Reactivities for anti-CD11b (ITGAM) Antibodies

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anti-Mouse (Murine) CD11b Antibodies:

anti-Rat (Rattus) CD11b Antibodies:

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Top referenced anti-CD11b Antibodies

Human Polyclonal CD11b Primary Antibody for FACS, ICC - ABIN409930 : Yin, Ahmad, Kosugi, Kawano, Avigan, Stone, Kharbanda, Kufe: Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein. in Cancer biology & therapy 2010 (PubMed)
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Human Polyclonal CD11b Primary Antibody for ICC, FACS - ABIN258322 : Chakrabarty, Jansen-West, Beccard, Ceballos-Diaz, Levites, Verbeeck, Zubair, Dickson, Golde, Das: Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)
Show all 17 Pubmed References
Human Monoclonal CD11b Primary Antibody for FACS, Func - ABIN1690733 : Leon, Contractor, Fuss, Marth, Lahey, Iwaki, la Sala, Hoffmann, Strober, Kelsall: Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
Show all 10 Pubmed References
Rat (Rattus) Monoclonal CD11b Primary Antibody for BR, IHC (fro) - ABIN2688912 : Issekutz, Issekutz: A major portion of polymorphonuclear leukocyte and T lymphocyte migration to arthritic joints in the rat is via LFA-1/MAC-1-independent mechanisms. in Clinical immunology and immunopathology 1993 (PubMed)
Show all 9 Pubmed References
Human Monoclonal CD11b Primary Antibody for FACS, Func - ABIN457369 : Ault, Springer: Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. in Journal of immunology (Baltimore, Md. : 1950) 1981 (PubMed)
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Human Polyclonal CD11b Primary Antibody for FACS, IF (p) - ABIN730918 : Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells. in Neuroscience 2012 (PubMed)
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Human Monoclonal CD11b Primary Antibody for FACS, Func - ABIN457346 : Brickson, Ji, Schell, Olabisi, St Pierre Schneider, Best: M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury. in Journal of applied physiology (Bethesda, Md. : 1985) 2003 (PubMed)
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Human Monoclonal CD11b Primary Antibody for FACS, IF - ABIN2688911 : Beller, Springer, Schreiber: Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. in The Journal of experimental medicine 1983 (PubMed)
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Human Monoclonal CD11b Primary Antibody for BR, IHC (fro) - ABIN1177001 : Flotte, Springer, Thorbecke: Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets. in The American journal of pathology 1983 (PubMed)
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Human Monoclonal CD11b Primary Antibody for BR, IHC (fro) - ABIN2688906 : Kishimoto, Jutila, Berg, Butcher: Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. in Science (New York, N.Y.) 1989 (PubMed)
Show all 8 Pubmed References

More Antibodies against CD11b Interaction Partners

Mouse (Murine) Integrin alpha M (ITGAM) interaction partners

results suggest that Mac-1 deficiency has little impact on the healing of small excisional and incisional wounds; moreover, the findings demonstrate that the effect of single genetic deficiencies on wound healing may markedly differ among wound models
These results indicated that integrin CD11b mediates alpha-synuclein-induced NOX2 (show CYBB Antibodies) activation through a RhoA (show RHOA Antibodies)-dependent pathway.
CD11b promotes the differentiation of osteoclasts induced by RANKL (show TNFSF11 Antibodies) through the Syk (show SYK Antibodies) signaling pathway.
These results showed that CR3 regulated Nox2 (show CYBB Antibodies) activation and dopaminergic neurodegeneration through a Src (show SRC Antibodies)-Erk (show EPHB2 Antibodies)-dependent pathway in a two pesticide-induced Parkinson's disease (PD) model, providing novel insights into the immune pathogenesis of PD.
Adhesive properties of the leukocyte integrin Mac-1 are not required for macrophage accumulation in adipose tissue. Instead, Mac-1 modulates inflammatory gene expression in macrophages.
Bone marrow mesenchymal stromal cells induce the rapid differentiation of CD11b+ myeloid cells from bone marrow progenitors, and such an activity requires the expression of nitric oxide synthase-2.
Mac-1(-/-) pups have reduced numbers of type I alveolar cells, respiratory failure and low survival.
data provide evidence that the NLRC4 (show NLRC4 Antibodies) inflammasome contributes to resistance through regulation of caspase-1 (show CASP1 Antibodies), IL-1beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies) in a CD11blowLy6Glow population of cells
CD11b+Gr-1 (show GSR Antibodies)+ myeloid-derived suppressor cells suppress T cells in an IFN-gamma (show IFNG Antibodies)- and nitric oxide-dependent manner to reduce atherosclerotic lesion development in LDLr (show LDLR Antibodies) deficient mice.
Mesenteric lymph node CD11b(-) CD103 (show ITGAE Antibodies)(+) PD-L1 (show CD274 Antibodies)(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (show TGFB1 Antibodies) activation.

Human Integrin alpha M (ITGAM) interaction partners

CD11b rs1143679 polymorphism appears to be associated with risk for SLE in the Han Chinese population, and may play an important role in the development of lupus nephritis.
discovered that OLFM4 (show OLFM4 Antibodies), CD11b, and ITGA2 (show ITGA2 Antibodies) are proteins that are overexpressed in both primary colon tumors and liver metastasis. These are colon cancer biomarkers with autoantigenic properties.
Up-regulation of granulocyte and monocyte CD11b during plasma separation was C5-dependent.
This study shown the ITGAM expression in Microglia and Astrocytes in stroke, Alzheimer's disease, and Lewy body dementia.
CD11b expression on polymorphonuclear leukocytes from patients with ankylosing spondylitis stimulated with lipopolysaccharide is not different to that of healthy controls.
The use of CD33 (show CD33 Antibodies)(+)CD11b(+)HLA-DR(-) cells as a predictive and prognostic biomarker.
Bone marrow mesenchymal stromal cells induce the rapid differentiation of CD11b+ myeloid cells from bone marrow progenitors, and such an activity requires the expression of nitric oxide synthase-2.
demonstrate for the first time a dependency of monocyte-platelet aggregates and CD11b expression on monocytes in the presence of atrial fibrillation (AF) and support the notion of a close relationship between AF, thrombogenesis and inflammation
Increased CD11b+ and CD200 (show CD200 Antibodies)+ monocytes in those with a strong presence of BVN indicate that BVN development may be associated with retinal injury and a VEGF (show VEGFA Antibodies)-mediated process that is either reflected or propelled by systemic changes in monocytes.
This study, we provide evidence supporting a crucial pathogenic role for alphaM-integrin (CD11b) in acute inflammatory demyelinating polyradiculoneuropathy mononuclear leukocyte trafficking.

Cow (Bovine) Integrin alpha M (ITGAM) interaction partners

These data describe the presence of specific pattern recognition receptor transcripts in the mRNA isolated from bovine neutrophil and show a CD11b-/Ca(2 (show CA2 Antibodies)+) dependent ROS (show ROS1 Antibodies) production
The molecular cloning and characterization of CD11b from cattle and its similarities to other species are presented.

Pig (Porcine) Integrin alpha M (ITGAM) interaction partners

CD11b (ITGAM) Antigen Profile

Antigen Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD11b (ITGAM)

integrin subunit alpha M (ITGAM) antibody
integrin alpha M (Itgam) antibody
integrin subunit alpha M (Itgam) antibody
integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM) antibody
integrin alpha-M (LOC100351865) antibody

C3bi antibody
CD11B antibody
CD11b/CD18 antibody
CR3 antibody
CR3A antibody
F730045J24Rik antibody
Ly-40 antibody
MAC-1 antibody
Mac-1a antibody
MAC1 antibody
MAC1A antibody
MO1A antibody
SLEB6 antibody

Protein level used designations for ITGAM

, , , , , , , , , , , , , , , , , , MAC-1 alpha subunit integrin alpha M integrin alpha-M CD11 antigen-like family member B CD11B (p170) CR-3 alpha chain Mac-1 alpha cell surface glycoprotein MAC-1 alpha subunit cell surface glycoprotein MAC-1 subunit alpha complement component receptor 3 alpha-a complement receptor type 3 leukocyte adhesion receptor MO1 macrophage antigen alpha antigen CD11b (p170) macrophage antigen alpha polypeptide neutrophil adherence receptor alpha-M subunit leukocyte integrin alpha-M chain complement receptor 3 leukocyte integrin alpha M

GENE ID	SPECIES
454069	Pan troglodytes
16409	Mus musculus
25021	Rattus norvegicus
3684	Homo sapiens
407124	Bos taurus
443217	Ovis aries
397459	Sus scrofa
489928	Canis lupus familiaris
100351865	Oryctolagus cuniculus
100135561	Cavia porcellus

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