The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010].
CD14
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Ouzounova, Lee, Piranlioglu, El Andaloussi, Kolhe, Demirci, Marasco, Asm, Chadli, Hassan, Thangaraju, Zhou, Arbab, Cowell, Korkaya: "Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade." in: Nature communications, Vol. 8, pp. 14979, (2018) (PubMed).
Gu, Werner, Bergmann, Whitcomb, Büchler, Fortunato: "Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis." in: Cell death & disease, Vol. 4, pp. e816, (2013) (PubMed).