The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012].
Pierog, Krishna, Yamniuk, Chauhan, DeSilva: "Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples." in: Journal of immunological methods, Vol. 416, pp. 124-36, (2015) (PubMed).
Aliases for CD16 Proteins
Fc fragment of IgG, low affinity IIa, receptor (Fcgr2a) Proteins Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A) Proteins Fc fragment of IgG receptor IIIb (FCGR3B) Proteins Fc fragment of IgG receptor IIIa (FCGR3A) Proteins Fc receptor, IgG, low affinity III (Fcgr3) Proteins Fc-gamma RIII (FCGR3) Proteins CD16 Proteins CD16b Proteins FCG3 Proteins Fcgr3 Proteins FCGR3 Proteins FCGR3@ Proteins Fcgr3a Proteins FCR-10 Proteins FCRIII Proteins FcRIII Proteins FCRIIIb Proteins