Browse our TXNRD3 Proteins (TXNRD3)

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• thioredoxin reductase 3 (TXNRD3)
• apoptosis-inducing factor 3 (LOC413958)
• thioredoxin reductase 3 L homeolog (txnrd3.L)
• thioredoxin reductase 3 (txnrd3)
• thioredoxin reductase 3 (Txnrd3)

• AI196535 protein
• MGC81848 protein
• MGC147163 protein
• Tgr protein
• TR2 protein
• Show all synonym aliases
• TRXR3 protein

thioredoxin reductase 3 , thioredoxin and glutathione reductase , thioredoxin glutathione reductase , thioredoxin reductase 2 , thioredoxin reductase TR2