Browse our anti-PAF1 (PAF1) Antibodies

Full name:: anti-Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) Antibodies (PAF1)

On www.antibodies-online.com are 65 Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) Antibodies from 15 different suppliers available. Additionally we are shipping PAF1 Proteins (3) and and many more products for this protein. A total of 73 PAF1 products are currently listed.

Synonyms:: 5730511K23Rik, AA675045, f23149_1, im:6906070, paf1, paf1l, pd2, RGD1306219, wu:fb80a09

list all antibodies	Gene Name	GeneID	UniProt
	PAF1	54623	Q8N7H5
	PAF1	54624	Q8K2T8
	PAF1	361531	Q4V886
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Top referenced anti-PAF1 Antibodies

Human Polyclonal PAF1 Primary Antibody for WB - ABIN153212 : Lin, Czapiga, Nini, Zhang, Simonds: Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function. in Molecular cancer research : MCR 2007 (PubMed)
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Human Polyclonal PAF1 Primary Antibody for ICC, IF - ABIN153213 : Chipumuro, Henriksen: The ubiquitin hydrolase USP22 contributes to 3'-end processing of JAK-STAT-inducible genes. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 (PubMed)

More Antibodies against PAF1 Interaction Partners

Human Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

a subset of enhancers can primarily modulate gene expression by controlling the release of paused Pol II (show 0 Antibodies) in a PAF1 (show PEX2 Antibodies)-dependent manner.
These results reveal ubiquitin-proteasome system regulation of Paf1 (show PEX2 Antibodies) and suggest downregulation of ubiquitin-proteasome system in elevating Paf1 (show PEX2 Antibodies)'s abundance in poorly differentiated cancers.
High PAF1 (show PEX2 Antibodies) expression is associated with ovarian cancer.
Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma.
Propose that degradation of MYC (show MYC Antibodies) limits the accumulation of MYC (show MYC Antibodies)/PAF1C complexes during transcriptional activation.
Mechanistic studies indicated that PAF1C could promote lung cancer cell proliferation through regulating c-MYC (show MYC Antibodies) transcription.
CNOT4 (show CNOT4 Antibodies) controls the degradation of chromatin-unbound PAF1 (show PEX2 Antibodies) via the 26S proteasome (show Psmd4 Antibodies).
this study found that Pol II (show 0 Antibodies)-associated factor 1 (PAF1 (show PEX2 Antibodies)) is a critical regulator of paused Pol II (show 0 Antibodies) release, that positive transcription elongation factor b (P-TEFb (show CDK9 Antibodies)) directly regulates the initial recruitment of PAF1 (show PEX2 Antibodies) complex (PAF1C) to genes, and that the subsequent recruitment of CDK12 (show CRKRS Antibodies) is dependent on PAF1C.
This study reveals an evolutionarily conserved role for PAF1 (show PEX2 Antibodies) as a regulator of promoter-proximal pausing by RNA Pol II (show 0 Antibodies) in all metazoans, including human.
PD2 is a novel cancer stem cell (CSC) maintenance protein, loss of which renders the CSCs more susceptible to drug-induced cell death.

Mouse (Murine) Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

link Paf1C with PolII (show 0 Antibodies) elongation and RNA processing indicates that Paf1C subunits could play roles in controlling transcript length through suppression of PolII (show 0 Antibodies) accumulation at transcription start site (TSS (show RPL38 Antibodies))-proximal pA sites
The PAF1 (show PEX2 Antibodies) complex is required for mammalian development, likely through regulation of H3K36me3, indicating a functional conservation of the PAF1 (show PEX2 Antibodies) complex from yeast to mammals in vivo.
As part of a cell-intrinsic transcriptional pathway, Paf1 (show PEX2 Antibodies) regulates neuronal migration in the brain.
MLL (show MLL Antibodies) interacts directly with the polymerase associated factor complex (PAFc) via Paf1 (show PEX2 Antibodies) and CTR9 (show CTR9 Antibodies). PAFc augments MLL (show MLL Antibodies) and MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) mediated transcriptional activation of Hoxa9 (show HOXA9 Antibodies) and their interaction is essential for leukemogenesis.
show that Paf1/PD2 is overexpressed in mouse embryonic stem cells (ESCs (show NR2E3 Antibodies)) and is involved in the maintenance of mouse ESCs (show NR2E3 Antibodies).

Zebrafish Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

The PAF1 complex differentially regulates cardiomyocyte specification.

PAF1 Antigen Profile

Antigen Summary

This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PAF1

PAF1 homolog, Paf1/RNA polymerase II complex component (PAF1) antibody
Paf1, RNA polymerase II complex component (Paf1) antibody
PAF1 homolog, Paf1/RNA polymerase II complex component (paf1) antibody
PAF1 homolog, Paf1/RNA polymerase II complex component L homeolog (paf1.L) antibody
RNA polymerase II-associated factor 1 homolog pseudogene (LOC100019208) antibody
RNA polymerase II-associated factor 1 homolog (LOC100161171) antibody
paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (paf1) antibody
RNA polymerase II-associated factor 1 homolog (LOC100639019) antibody
RNA polymerase II-associated factor 1 homolog (LOC100650306) antibody
PAF1 homolog, Paf1/RNA polymerase II complex component (Paf1) antibody
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (PAF1) antibody

5730511K23Rik antibody
AA675045 antibody
f23149_1 antibody
im:6906070 antibody
paf1 antibody
paf1l antibody
pd2 antibody
RGD1306219 antibody
wu:fb80a09 antibody

Protein level used designations for PAF1

RNA polymerase II-associated factor 1 homolog , pancreatic differentiation protein 2 , PD2-like protein , paf1, RNA polymerase II associated factor, homolog, like , Paf1, RNA polymerase II associated factor, homolog

GENE ID	SPECIES
54623	Homo sapiens
54624	Mus musculus
394974	Xenopus (Silurana) tropicalis
446278	Xenopus laevis
553020	Danio rerio
100019208	Monodelphis domestica
100161171	Acyrthosiphon pisum
100172552	Pongo abelii
100194999	Salmo salar
100411768	Callithrix jacchus
100465029	Ailuropoda melanoleuca
100514194	Sus scrofa
100543667	Meleagris gallopavo
100594485	Nomascus leucogenys
100639019	Amphimedon queenslandica
100650306	Bombus terrestris
361531	Rattus norvegicus
528744	Bos taurus
100713356	Cavia porcellus

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