PRMT5 Proteins
10 Protein Arginine Methyltransferase 5 (PRMT5) Proteins from 5 manufacturers are available on www.antibodies-online.com.
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Protein Arginine Methyltransferase 5 (PRMT5) (AA 1-637) protein (GST tag) Protein
1
Protein Arginine Methyltransferase 5 (PRMT5) protein (DYKDDDDK Tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (AA 1-637) protein (His tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (His tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (His tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (AA 531-637) protein (GST tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (DYKDDDDK Tag,His tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) protein (GST tag) Protein
Protein Arginine Methyltransferase 5 (PRMT5) protein (GST tag) Protein
PRMT5 Protein Profile
Protein Summary
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3)\; such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR\; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity (By similarity). Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation (By similarity). Methylates HOXA9 (By similarity).
Alternative names and synonyms associated with PRMT5
- protein arginine methyltransferase 5 (PRMT5) antibody
- protein arginine N-methyltransferase 5 (Prmt5) antibody
- protein arginine methyltransferase 5 (Prmt5) antibody
- protein arginine methyltransferase 5 (prmt5) antibody
- protein arginine methyltransferase 5 L homeolog (prmt5.L) antibody
- putative arginine N-methyltransferase, type II (PRMT5) antibody
- Skb1 family protein (prmt5) antibody
- protein arginine N-methyltransferase 5 (LOC100115766) antibody
- Protein arginine N-methyltransferase 5 (prmt-5) antibody
- DDBDRAFT_0187422 antibody
- DDBDRAFT_0235403 antibody
- DDB_0187422 antibody
- DDB_0235403 antibody
- hrmt1l5 antibody
- hsl7 antibody
- ibp72 antibody
- jbp1 antibody
- NV18830 antibody
- si:zc14a17.2 antibody
- skb1 antibody
- skb1hs antibody
- wu:fb95f10 antibody
- zgc:110669 antibody
Protein level used designations for PRMT5
72 kDa ICln-binding protein , HMT1 hnRNP methyltransferase-like 5 , SKB1 homolog , histone-arginine N-methyltransferase PRMT5 , jak-binding protein 1 , protein arginine N-methyltransferase 5 , shk1 kinase-binding protein 1 homolog , protein arginine methyltransferase 5 , Jak-binding protein 1 , putative arginine N-methyltransferase, type II , protein arginine methyltransferase , protein arginine N-methyltransferase 5-like
| GENE ID | SPECIES |
|---|---|
| 10419 | Homo sapiens |
| 100583805 | Nomascus leucogenys |
| 27374 | Mus musculus |
| 364382 | Rattus norvegicus |
| 368664 | Danio rerio |
| 515594 | Bos taurus |
| 100173581 | Pongo abelii |
| 452789 | Pan troglodytes |
| 480242 | Canis lupus familiaris |
| 495515 | Xenopus laevis |
| 712718 | Macaca mulatta |
| 5068851 | Leishmania infantum JPCM5 |
| 8626071 | Dictyostelium discoideum AX4 |
| 100024287 | Monodelphis domestica |
| 100052729 | Equus caballus |
| 100115766 | Nasonia vitripennis |
| 100144380 | Oryzias latipes |
| 100145788 | Xenopus (Silurana) tropicalis |
| 100294711 | Sus scrofa |
| 100357415 | Oryctolagus cuniculus |
| 100473723 | Ailuropoda melanoleuca |
| 100555438 | Anolis carolinensis |
| 175717 | Caenorhabditis elegans |
| 100731218 | Cavia porcellus |
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