PRMT5 Proteins

10 Protein Arginine Methyltransferase 5 (PRMT5) Proteins from 6 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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10 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3089077
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3089078
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3136486
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Wheat germ (Source)
Pubmed ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1316333
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Baculovirus (Source)
ReactivityHuman
Application EAA, ScA
Order details Cat. No. ABIN2669658
$513.33
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1316335
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729673
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Baculovirus infected Insect Cells, Insect cells (Sf9) (Source)
ReactivityHuman
Application WB
Order details Cat. No. ABIN6700421
$317.90
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
Recombinant Protein, Human Cells (Source), Purity > 85 % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2003914
Pubmed
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Baculovirus infected Insect Cells, Insect cells (Sf9) (Source)
ReactivityHuman
Application WB
Order details Cat. No. ABIN6700420
$618.20
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
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PRMT5 Protein Profile

Protein Summary

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3)\; such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR\; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity (By similarity). Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation (By similarity). Methylates HOXA9 (By similarity).

Alternative names and synonyms associated with PRMT5

  • protein arginine methyltransferase 5 (PRMT5) antibody
  • protein arginine N-methyltransferase 5 (Prmt5) antibody
  • protein arginine methyltransferase 5 (Prmt5) antibody
  • protein arginine methyltransferase 5 (prmt5) antibody
  • protein arginine methyltransferase 5 L homeolog (prmt5.L) antibody
  • putative arginine N-methyltransferase, type II (PRMT5) antibody
  • Skb1 family protein (prmt5) antibody
  • protein arginine N-methyltransferase 5 (LOC100115766) antibody
  • Protein arginine N-methyltransferase 5 (prmt-5) antibody
  • DDBDRAFT_0187422 antibody
  • DDBDRAFT_0235403 antibody
  • DDB_0187422 antibody
  • DDB_0235403 antibody
  • hrmt1l5 antibody
  • hsl7 antibody
  • ibp72 antibody
  • jbp1 antibody
  • NV18830 antibody
  • si:zc14a17.2 antibody
  • skb1 antibody
  • skb1hs antibody
  • wu:fb95f10 antibody
  • zgc:110669 antibody

Protein level used designations for PRMT5

72 kDa ICln-binding protein , HMT1 hnRNP methyltransferase-like 5 , SKB1 homolog , histone-arginine N-methyltransferase PRMT5 , jak-binding protein 1 , protein arginine N-methyltransferase 5 , shk1 kinase-binding protein 1 homolog , protein arginine methyltransferase 5 , Jak-binding protein 1 , putative arginine N-methyltransferase, type II , protein arginine methyltransferase , protein arginine N-methyltransferase 5-like

GENE ID SPECIES
10419 Homo sapiens
100583805 Nomascus leucogenys
27374 Mus musculus
364382 Rattus norvegicus
368664 Danio rerio
515594 Bos taurus
100173581 Pongo abelii
452789 Pan troglodytes
480242 Canis lupus familiaris
495515 Xenopus laevis
712718 Macaca mulatta
5068851 Leishmania infantum JPCM5
8626071 Dictyostelium discoideum AX4
100024287 Monodelphis domestica
100052729 Equus caballus
100115766 Nasonia vitripennis
100144380 Oryzias latipes
100145788 Xenopus (Silurana) tropicalis
100294711 Sus scrofa
100357415 Oryctolagus cuniculus
100473723 Ailuropoda melanoleuca
100555438 Anolis carolinensis
175717 Caenorhabditis elegans
100731218 Cavia porcellus
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