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anti-Mouse (Murine) Kallikrein 7 Antibodies:
anti-Rat (Rattus) Kallikrein 7 Antibodies:
anti-Human Kallikrein 7 Antibodies:
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Human Polyclonal Kallikrein 7 Primary Antibody for IHC (p), IHC - ABIN441432
Sheets, Massey, Cronk, Iafrati, Herman: Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine. in Journal of translational medicine 2016
Show all 2 Pubmed References
Human Polyclonal Kallikrein 7 Primary Antibody for IF (p), IHC (p) - ABIN676028
Yamamoto, Yamamoto, Yamada, Hasegawa, Hongo, Oda, Amizuka: Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars. in Histochemistry and cell biology 2014
Ablation of KLK7 is not sufficient to rescue the lethal effect of LEKTI (show SPINK5 Antibodies)-deficiency. Double deficiency of both KLK7 and KLK5 completely rescues Netherton Syndrome (show SPINK5 Antibodies)-like phenotype.
Higher hK7 expression is associated with cervical adenocarcinomas
Prolonged Klk7 neutralization provokes profound abnormalities in Klk7 function, due to pH-induced high serine protease (show F2 Antibodies) activity that degrades lipid processing enzymes and corneodesmosomes proteins.
KLK7 is differentially expressed in lesional biopsy specimens from patients with atopic eczema relative to normal skin
impaired KLK7 secretion from lamellar granules and increased LEKTI expression could underlie the insufficient activation of KLK in atopic dermatitis.
Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells
Korean X-linked ichthyosis (show LBR Antibodies) patients exhibited unimpaired skin barrier function and frequent association with the KLK7 gene polymorphism, which may differentiate them from Western X-linked ichthyosis (show LBR Antibodies) patients.
This report demonstrates that concurrent loss of KLK5 (show KLK5 Antibodies) and KLK7 associates with a poor clinical outcome in Squamous-Cell Carcinoma and could therefore serve as prognostic marker in this disease.
Data demonstrate that elevated levels of KLK6, KLK7 and KLK9 proteins are associated with poor glioblastoma patients survival.
Our findings suggest that serum KLK7 may be a valuable diagnostic biomarker for cervical cancer, and may help to determine the individual prognosis of these patients.
KLK6 (show KLK1 Antibodies) and KLK7 mRNA and protein overexpression is directly associated with early-stage ovarian tumors.
Proteolytic cleavage of midkine (show MDK Antibodies), CYR61 (show CYR61 Antibodies), and tenascin-C (show TNC Antibodies) govern the pathophysiological roles of KLK7.
Early-stage oral squamous cell carcinoma and high KLK7 mRNA levels were correlated with the rs10581213(wt/ins + ins/ins (show INS Antibodies)) genotypes
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
kallikrein 7 (chymotryptic, stratum corneum)
, protease, serine, 6
, serine protease 6
, stratum corneum chymotryptic enzyme
, kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
, signal protein