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Human Prostate Specific Antigen Protein expressed in Human - ABIN934764
Harris, Lenz, Hankey, MacVittie, Farese, Nakajima, Hasumi, Mann: Products of anti-CD3/anti-CD28 activated lymphocytes induce differentiation and maturation of dendritic cells and have adjuvant-like activity in vitro and in vivo. in Clinical immunology (Orlando, Fla.) 2008
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Human Prostate Specific Antigen Protein expressed in Human - ABIN934794
Marshall, Rudnick, McCarthy, Mateo, Harris, McCauley, Snyder: Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine. in Vaccine 2005
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the concentrations of insulin (show INS Proteins), IGF-1 (show IGF1 Proteins), IGFBP-3 (show IGFBP3 Proteins) and their association with prostate size in patients with BPH (show GLI3 Proteins)
Data suggest that occurrence of PSA failure was associated with increased risk of all-cause mortality (ACM) only in men with no or minimal, but not moderate-to-severe, comorbidity.
Annexin A2 (ANXA2) and prostate-specific antigen (PSA) proteins measured from biopsy tumour regions are unlikely to be good biomarkers for prediction of the clinical outcome of prostate cancer presenting with apparently localized disease.
Microenvironmental acidity determines qualitatively and quantitatively the release of extracellular vesicles by malignant prostate tumors. This leads to the spill-over of nanovesicles into the peripheral blood of prostate cancer patients, where the levels of tumor biomarkers expressed by exosomes, such as PSA-exosomes, may represent a novel, non-invasive diagnostic tool.
Promoter methylation of MCAM, ERalpha and ERbeta have a potential to be utilized as biomarker for the early detection of prostate cancer (PC) as their sensitivity and specificity seem to be better than serum PSA.
Data suggest no influence of chronic periodontitis treatment on PSA levels in asymptomatic men.
Circulating total PSA levels were strongly associated to leukocyte telomere length in a national sample of men without prostate cancer.
I might also point out that whether a particular surgical procedure did more good than harm at that time was highly dependent on whether it was conducted with good sterile procedure. PSA screening is a contemporary example of this historical lesson
Data show that forkhead box M1 protein (FOXM1) directly binds to the FHK binding motifs in the prostate specific antigen (PSA) promoter/enhancer regions.
Study suggests that the prognostic value of PSA declines in heavily treated patients receiving enzalutamide
Nucleocytoplasmic transfer of cyclin dependent kinase 5 (show CDK5 Proteins) and its binding to puromycin-sensitive aminopeptidase (show NPEPPS Proteins) in Dictyostelium discoideum
findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity
These data indicate that PSA (show NPEPPS Proteins) may play a role in limiting MHC class I Ag presentation in dendritic cells in vivo but that it is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (show GLA Proteins).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
, prostate specific antigen
, prostate-specific antigen
, kallikrein-related peptidase 3
, S1 kallikrein
, glandular kallikrein-3, submandibular
, kallikrein 1-related peptidase c10-like 2
, kallikrein 3
, submaxillary gland S1 kallikrein
, tissue kallikrein
, cytosol alanyl aminopeptidase
, puromycin-sensitive aminopeptidase