Prostate Specific Antigen Protein (PSA) (Fc Tag)

Catalog No. ABIN6964284

Product Details

Target: Prostate Specific Antigen (PSA)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Prostate Specific Antigen protein is labelled with Fc Tag.

Sequence: KLK3(Ile25-Phe261)+hFc(Glu99-Ala330)

Characteristics: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -80 °C

Storage Comment: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Expiry Date: 12 months

Target Details

Target: Prostate Specific Antigen (PSA)

Alternative Name: KLK3 (PSA Products)

Synonyms: APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein

Background: Synonymes: APS, hK3, KLK2A1, PSA
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]

Molecular Weight: 51.7 kDa

UniProt: P07288

Pathways: Complement System