Prostate Specific Antigen Protein (PSA) (AA 25-261) (His tag)
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- Target See all Prostate Specific Antigen (PSA) Proteins
- Prostate Specific Antigen (PSA)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-261
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Prostate Specific Antigen protein is labelled with His tag.
- Purpose
- Recombinant Human PSA/KLK3 Protein (aa 25-261, His Tag)
- Sequence
- Ile25-Pro261
- Characteristics
- Recombinant Human Kallikrein-3/Prostate-specific antigen is produced by our Mammalian expression system and the target gene encoding Ile25-Pro261 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PSA Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHcl, 150 mM NaCl,1 mM CaCl2, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Prostate Specific Antigen (PSA)
- Alternative Name
- PSA/KLK3 (PSA Products)
- Synonyms
- APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein
- Background
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Background: KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Synonym: APS,Hk3,KLK2A1,PSA,Prostate-Specific Antigen, PSA, Gamma-Seminoprotein, Seminin, Kallikrein-3, P-30 Antigen, Semenogelase,
- Molecular Weight
- 27.1 kDa
- UniProt
- P07288
- Pathways
- Complement System
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