DENND1C Proteins

(DENN/MADD Domain Containing 1C (DENND1C))

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2\; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010].

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DENND1C Protein (AA 1-786) (His tag)

custom-made DENND1C Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Dennd1c Protein, UniprotID Q8CFK6

3 images

Catalog No. ABIN7559309

Details

DENND1C Protein (AA 1-801) (His tag)

custom-made DENND1C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant DENND1C Protein, UniprotID Q8IV53

3 images

Catalog No. ABIN7553634

Details

DENND1C Protein (AA 1-786) (Strep Tag)

custom-made DENND1C Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3125968

Details

DENND1C Protein (AA 1-801) (Strep Tag)

custom-made DENND1C Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3092071