Browse our anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) Antibodies

Full name:: anti-Poly (ADP-Ribose) Polymerase 2 Antibodies (PARP2)

On www.antibodies-online.com are 93 Poly (ADP-Ribose) Polymerase 2 (PARP2) Antibodies from 20 different suppliers available. Additionally we are shipping Poly (ADP-Ribose) Polymerase 2 Proteins (7) and Poly (ADP-Ribose) Polymerase 2 Kits (6) and many more products for this protein. A total of 113 Poly (ADP-Ribose) Polymerase 2 products are currently listed.

Synonyms:: ADPRT-2, Adprt2, adprtl2, ADPRTL3, APP, ARTD2, Aspartl2, ATPARP1, C78626, cb996, pADPRT-2, PARP-2, PARP1, poly(ADP-ribose) polymerase, POLY(ADP-RIBOSE) POLYMERASE 1, poly(ADP-ribose) polymerase 2, PP, T14P8.19, T14P8_19

list all antibodies	Gene Name	GeneID	UniProt
	PARP2	10038	Q9UGN5
	PARP2	11546	O88554
	PARP2	290027
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Most Popular Reactivities for anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) Antibodies

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anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

40 WB Antibodies

anti-Rat (Rattus) Antibodies:

5 WB Antibodies

All available anti-Poly (ADP-Ribose) Polymerase 2 Antibodies

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Relevant Pathways for anti-Poly (ADP-Ribose) Polymerase 2 Antibodies

DNA Damage Repair

More product categories related to Poly (ADP-Ribose) Polymerase 2 Antibody

Top referenced anti-Poly (ADP-Ribose) Polymerase 2 Antibodies

Human Polyclonal PARP2 Primary Antibody for ELISA, WB - ABIN250990 : Kofler, Otsuka, Zhang, Noppens, Grafe, Koh, Dawson, de Murcia, Hurn, Traystman: Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005 (PubMed)
Human Polyclonal PARP2 Primary Antibody for WB - ABIN151360 : Ovadje, Ammar, Guerrero, Arnason, Pandey: Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways. in Oncotarget 2016 (PubMed)
Human Polyclonal PARP2 Primary Antibody for ChIP, IP - ABIN2668807 : Hanzlikova, Gittens, Krejcikova, Zeng, Caldecott: Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin. in Nucleic acids research 2016 (PubMed)

More Antibodies against Poly (ADP-Ribose) Polymerase 2 Interaction Partners

Human Poly (ADP-Ribose) Polymerase 2 (PARP2) interaction partners

Report a requirement for PARP2 in stabilizing replication forks that encounter base excision repair (BER) intermediates through Fbh1 (show FBXO18 Antibodies)-dependent regulation of Rad51 (show RAD51 Antibodies). Whereas PARP2 is dispensable for tolerance of cells to single stranded breaks or homologous recombination dysfunction, it is redundant with PARP1 (show PARP1 Antibodies) in BER.
PARP2 specifically limits the accumulation of the resection barrier factor 53BP1 (show TP53BP1 Antibodies) at DNA damage sites, allowing efficient CtIP (show RBBP8 Antibodies)-dependent DNA end-resection
either PARP1 (show PARP1 Antibodies) or PARP2 are sufficient for near-normal XRCC1 (show XRCC1 Antibodies) recruitment at oxidative single-strand breaks
Studies indicate that poly(ADP-ribose) polymerase 2 (PARP2) is involved in the differentiation of several cell types, including erythrocytes, T cells and adipocytes.
Findings indicate that Increased poly(ADP-ribose) polymerase-2 (PARP-2) expression and loss of micrRNA miR (show MLXIP Antibodies)-149 expression are involved in the pathogenesis of hepatocellular carcinomas (HCC (show FAM126A Antibodies)) and are poor prognosis factors in patients with HCC (show FAM126A Antibodies).
Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1 (show PARP1 Antibodies)/2 and tankyrase 1 (show TNKS Antibodies)/2 inhibitor which has the advantage of targeting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling addicted tumors.
The initial affinity between the PARP1 (show PARP1 Antibodies), PARP2 and the DNA damaged site appears to influence both the size of the Poly(ADP-Ribose) synthesized and the time of residence of PARylated PARP1 (show PARP1 Antibodies) and PARP2 on DNA damages.
Our data suggest for the first time that a SNP in PARP2, rs878156, may together with other genetic variants modulate cancer specific survival in breast cancer patients depending on chemotherapy
Our study differentiates the functions of PARP-2 domains from those of PARP-1 (show PARP1 Antibodies), the other major DDR (show DDR1 Antibodies)-PARP (show COL11A2 Antibodies), and highlights the specialization of the multi-domain architectures of DDR (show DDR1 Antibodies)-PARPs.
Interaction of PARP-2 with AP site containing DNA

Mouse (Murine) Poly (ADP-Ribose) Polymerase 2 (PARP2) interaction partners

PARP2 protein deficiency protected mice from Concanavalin A -induced Liver Damage.
Activation of either PARP-1 (show PARP1 Antibodies) or -2 is likely to play a role in muscle protein catabolism via oxidative stress, NF-kappaB (show NFKB1 Antibodies) signaling, and enhanced proteasomal degradation in cancer-induced cachexia.
PARP1 (show PARP1 Antibodies)/2 inhibitor simmiparib causes growth inhibition in cancer cell- or tissue-derived xenografts in nude mice.
The findings highlight specific non-overlapping functions of PARP1 (show PARP1 Antibodies) and PARP2 at H2AX (show H2AFX Antibodies)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 (show PARP1 Antibodies) in nonhomologous end-joining-deficient cells.
Data show reduced tumor burden through increased oxidative stress in lung adenocarcinoma cells of PARP-1 (show PARP1 Antibodies) and PARP-2 knockout mice.
PARP-2 has an essential role in erythropoiesis by limiting replicative stress in erythroid progenitors.
PARP-1 (show PARP1 Antibodies) and -2 play a role in cancer-induced cachexia, thus selective pharmacological inhibition of PARP-1 (show PARP1 Antibodies) and -2 may be of interest in clinical settings
the depletion of PARP-2 leads to lower HDL (show HSD11B1 Antibodies) levels which represent a risk factor to cardiovascular diseases.
This study represents the first description of a significant role for PARP-2 in neuroinflammation and neurological dysfunction in Experimental autoimmune encephalomyelitis
our data show that PARP-2 can directly regulate base excision repair proteins

Arabidopsis thaliana Poly (ADP-Ribose) Polymerase 2 (PARP2) interaction partners

We found that larger deletions of >20 bp predominated after DSB repair in ku80 (show XRCC5 Antibodies) and ku80 (show XRCC5 Antibodies) parp1 parp2 mutants, corroborating with a role of KU in preventing DSB end resection. Deletion lengths did not significantly differ between ku80 (show XRCC5 Antibodies) and ku80 (show XRCC5 Antibodies) parp1 parp2 mutants, suggesting that a KU- and PARP (show PARP1 Antibodies)-independent b-NHEJ mechanism becomes active in these mutants.
we have found that although plant PARPs and PARGs have partially overlapping functions Arabidopsis PARP2 and PARG1 play the predominant roles in plant poly(ADP-ribosyl)ation during DNA damage and immune responses.
whilst all isoforms of PARP (show PARP1 Antibodies) were localized to the nucleus they are also present in non-nuclear locations with parp1 and parp3 (show PARP3 Antibodies) also localised in the cytosol, and parp2 also present in the mitochondria
Studies indicate that a massive and rapid accumulation of a massive and rapid accumulation poly(ADP-ribose) polymerases AtPARP1 and AtPARP2 transcripts was observed upon treatment with ionizing radiation and reactive oxigen species (ROS (show ROS1 Antibodies)).
Poly(ADP-ribose)polymerase (show PARP1 Antibodies) activity controls plant growth by promoting leaf cell number.
Evidence suggests a link between the glutathione pool and PARP (show PARP1 Antibodies) expression and activity that is perhaps related to the distribution of intracellular glutathione between the cytoplasm and the nucleus. [PARP2]

Poly (ADP-Ribose) Polymerase 2 (PARP2) Antigen Profile

Antigen Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Alternative names and synonyms associated with Poly (ADP-Ribose) Polymerase 2 (PARP2)

poly(ADP-ribose) polymerase 2 (PARP2) antibody
poly (ADP-ribose) polymerase family, member 2 (Parp2) antibody
poly (ADP-ribose) polymerase 2 (Parp2) antibody
poly (ADP-ribose) polymerase family, member 2 (parp2) antibody
poly(ADP-ribose) polymerase 2 S homeolog (parp2.S) antibody
poly(ADP-ribose) polymerase 2 (Parp2) antibody
poly(ADP-ribose) polymerase (PARP2) antibody

ADPRT-2 antibody
Adprt2 antibody
adprtl2 antibody
ADPRTL3 antibody
APP antibody
ARTD2 antibody
Aspartl2 antibody
ATPARP1 antibody
C78626 antibody
cb996 antibody
pADPRT-2 antibody
PARP-2 antibody
PARP1 antibody
poly(ADP-ribose) polymerase antibody
POLY(ADP-RIBOSE) POLYMERASE 1 antibody
poly(ADP-ribose) polymerase 2 antibody
PP antibody
T14P8.19 antibody
T14P8_19 antibody

Protein level used designations for PARP2

ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2 , ADP-ribosyltransferase diphtheria toxin-like 2 , ADPRT-2 , NAD(+) ADP-ribosyltransferase 2 , hPARP-2 , poly (ADP-ribose) polymerase family, member 2 , poly (ADP-ribosyl) transferase-like 2 , poly [ADP-ribose] polymerase 2 , poly(ADP-ribose) synthetase , poly[ADP-ribose] synthase 2 , poly[ADP-ribose] synthetase 2 , ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2 , mPARP-2 , pADPRT-2 , poly (ADP-ribose) polymerase 2 , poly [ADP-ribose] polymerase 2-like , Poly[ADP-ribose] synthase 2

GENE ID	SPECIES
10038	Homo sapiens
11546	Mus musculus
290027	Rattus norvegicus
386773	Danio rerio
446370	Xenopus laevis
465197	Pan troglodytes
475392	Canis lupus familiaris
701955	Macaca mulatta
100452137	Pongo abelii
505828	Bos taurus
100720452	Cavia porcellus
828049	Arabidopsis thaliana
100518917	Sus scrofa
100072572	Equus caballus

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Show all anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) Antibodies with Pubmed References