PARP2 antibody (AA 1-207)

Catalog No. ABIN2745554

This Rabbit Polyclonal antibody specifically detects PARP2 in WB, ICC, IHC and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for PARP2 antibody (AA 1-207) (ABIN2745554)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-PARP2 Antibody

Binding Specificity: AA 1-207

Purpose: anti-PARP-2 [ARTD2] (mouse), pAb

Specificity: Recognizes mouse PARP-2. Cross-reacts weakly with human PARP-2.

Cross-Reactivity (Details): Cross-reacts weakly with human PARP-2.

Characteristics: Polyclonal Antibody. Recognizes mouse PARP-2. Cross-reacts weakly with human PARP-2. Source: Rabbit. Applications: ICC, IHC, IP, WB. Liquid. Contains 0.1 % sodium azide. PARP-2 (ARTD2) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Immunogen: Recombinant mouse PARP-2 [ARTD2] (aa 1-207).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Contains 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP-2 [ARTD2]

Background:

Alternate Names/Synonyms: Poly(ADP-ribose) Polymerase 2, ADP-ribosyltransferase Diphtheria Toxin-like 2, NAD(+) ADP-ribosyltransferase 2

Product Description: PARP-2 (ARTD2) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

UniProt: O88554

Pathways: DNA Damage Repair