Browse our Polymerase (DNA Directed), eta Proteins (POLH)

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA\; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum.

• polymerase (DNA directed), eta S homeolog (polh.S)
• DNA polymerase eta (POLH)
• polymerase (DNA directed), eta (polh)
• DNA polymerase eta (Tb10.70.6190)
• putative DNA polymerase eta (LINJ_21_0690)
• Show all gene names
• polymerase (DNA directed), eta (Polh)
• DNA polymerase eta (LOC100443019)
• DNA polymerase eta (polh)
• DNA polymerase eta (Polh)
• polymerase (DNA directed), eta (RAD 30 related) (Polh)

• fc50a12 protein
• POLH protein
• RAD30 protein
• RAD30A protein
• wu:fc50a12 protein
• Show all synonym aliases
• XP-V protein
• XPV protein
• zgc:136881 protein
• zgc:152642 protein

DNA-directed DNA polymerase eta , DNA polymerase eta , polymerase (DNA directed), eta , DNA polymerase eta-like , polymerase eta , RAD30 homolog A , xeroderma pigmentosum variant type protein , polymerase (DNA directed), eta (RAD 30 related) , xeroderma pigmentosum variant type protein homolog