ECSIT Homolog (ECSIT) (N-Term) Peptide
Quick Overview for ECSIT Homolog (ECSIT) (N-Term) Peptide (ABIN976118)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- EPWLVPRPPE PQRKPIKVPA MHEDSFKPSG NRERDKASFL NAVRSFGAHN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ecsit Antibody(ARP37175_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ECSIT (ECSIT Homolog (ECSIT))
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Background
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Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Irak1,Map3k1,SMURF1,TRAF6,Traf6
Protein Size: 435 -
Molecular Weight
- 50 kDa
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Gene ID
- 26940
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NCBI Accession
- NM_012029, NP_036159
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UniProt
- Q9QZH6
Target
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