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EED Products

(Embryonic Ectoderm Development (EED))

Categories

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured EED Categories

EED Antibodies

High quality antibodies with extensive validation data.

EED ELISA Kits

Reliable ELISA kits for a wide range of species.

EED Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EED Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IF
Validations
  • (2)
  • (8)
Cat. No. ABIN2776407
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6139940
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN522175
Quantity 100 μg
Datasheet Datasheet

Recommended EED ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rabbit
Analytical Method Quantitative
Validations
Cat. No. ABIN510263
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN770737
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN776698
Quantity 96 tests
Datasheet Datasheet

Recommended EED Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1352339
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122765
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352337
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our EED products

Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." in: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

Lin, Huang, Chang, Chang, Yen, Lee, Chang, Liu, Chang: "Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2." in: BMC cancer, Vol. 16, pp. 583, (2016) (PubMed).

Martin, Popov, Aguilo, OLoghlen, Raguz, Snijders, Dharmalingam, Li, Thymiakou, Carroll, Zeisig, So, Peters, Episkopou, Walsh, Gil: "Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation." in: The EMBO journal, Vol. 32, Issue 7, pp. 982-95, (2013) (PubMed).

Guil, Soler, Portela, Carrère, Fonalleras, Gómez, Villanueva, Esteller: "Intronic RNAs mediate EZH2 regulation of epigenetic targets." in: Nature structural & molecular biology, Vol. 19, Issue 7, pp. 664-70, (2012) (PubMed).

Tae, Karkhanis, Velasco, Yaneva, Erdjument-Bromage, Tempst, Sif: "Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes." in: Nucleic acids research, Vol. 39, Issue 13, pp. 5424-38, (2011) (PubMed).

Rakotobe, Violot, Hong, Gouet, Boulanger: "Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED." in: Virology journal, Vol. 5, pp. 32, (2008) (PubMed).

Synonyms and alternative names related to EED

embryonic ectoderm development (eed), embryonic ectoderm development (EED), embryonic ectoderm development S homeolog (eed.S), microRNA 6755 (MIR6755), embryonic ectoderm development (Eed), embryonic ectoderm development L homeolog (eed.L), EED, eed, ENSMUSG00000039373, heed, HEED, l(7)5Rn, l7Rn5, lusk, psXEED, wait1, WAIT1, Xeed, Xeed-A, Xeed-B, zgc:112509

Protein level used designations for EED

  • polycomb protein eed
  • embryonic ectoderm development
  • WD protein associating with integrin cytoplasmic tails 1
  • polycomb protein EED
  • embryonic ectoderm development protein variant 1
  • polycomb protein eed-B
  • embryonic ectoderm development protein
  • lethal, Chr 7, Rinchik 5
  • polycomb protein eed-A
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