Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

EEF2K Products

(Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Categories

Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. {ECO:0000269|PubMed:14709557, ECO:0000269|PubMed:9144159}.

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured EEF2K Categories

EEF2K Antibodies

High quality antibodies with extensive validation data.

EEF2K ELISA Kits

Reliable ELISA kits for a wide range of species.

EEF2K Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EEF2K Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN6261444
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (4)
Cat. No. ABIN2856812
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN526147
Quantity 50 μg
Datasheet Datasheet

Recommended EEF2K ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966603
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380120
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended EEF2K Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1352365
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5570623
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092342
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our EEF2K products

Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

Usui, Nijima, Sakatsume, Otani, Kameshima, Okada, Yamawaki: "Eukaryotic elongation factor2 kinase controls proliferation and migration of vascular smooth muscle cells." in: Acta physiologica (Oxford, England), (2014) (PubMed).

Liu, Zhang, Wu, Zhou, Ren, Yang, Ming, Chen, Wang, Zhang, Yang: "Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma." in: PLoS ONE, Vol. 8, Issue 11, pp. e81345, (2013) (PubMed).

Browne, Finn, Proud: "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12220-31, (2004) (PubMed).

Browne, Proud: "A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2986-97, (2004) (PubMed).

Knebel, Haydon, Morrice, Cohen: "Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways." in: The Biochemical journal, Vol. 367, Issue Pt 2, pp. 525-32, (2002) (PubMed).

Synonyms and alternative names related to EEF2K

eukaryotic elongation factor 2 kinase (EEF2K), eukaryotic elongation factor-2 kinase (Eef2k), eukaryotic elongation factor 2 kinase (eef2k), eukaryotic elongation factor 2 kinase (LOC101930123), eukaryotic elongation factor 2 kinase (Eef2k), C86191, cb365, eEF-2 kinase, eEF-2K, fa04b08, HSU93850, SMEF2K, wu:fa04b08, zgc:100973

Protein level used designations for EEF2K

  • calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
  • calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase
  • calmodulin-dependent protein kinase III
  • eEF-2 kinase
  • elongation factor-2 kinase
  • eukaroytic elongation factor 2 kinase
  • eukaryotic elongation factor 2 kinase
  • eukaryotic elongation factor-2 kinase
  • eukaroytic elongation factor 2 kinase-like
  • eEF-2K
  • elongation factor 2 kinase
  • Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
You are here:
Support