EFNB2A antibody (AA 163-194)
EFNB2A
Reactivity: Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
(2 references)-
- Target See all EFNB2A products
- EFNB2A
- Binding Specificity
- AA 163-194
- Reactivity
- Zebrafish (Danio rerio)
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DANRE efnb2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-194 amino acids from the Central region of DANRE efnb2a.
- Isotype
- Ig Fraction
-
- Application Notes
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
-
-
: "Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling." in: Developmental biology, Vol. 234, Issue 2, pp. 470-82, (2001) (PubMed).
: "Eph signaling is required for segmentation and differentiation of the somites." in: Genes & development, Vol. 12, Issue 19, pp. 3096-109, (1998) (PubMed).
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: "Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling." in: Developmental biology, Vol. 234, Issue 2, pp. 470-82, (2001) (PubMed).
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- Target
- EFNB2A
- Background
- Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration (By similarity).
- Molecular Weight
- 36724
- NCBI Accession
- NP_571098
- UniProt
- O73874
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