Browse our anti-ADAM12 (ADAM12) Antibodies

Zebrafish ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

1. results suggest that adam12 plays a significant role in the regulation of body growth during juvenile stage in zebrafish, although the precise molecular mechanisms await further study.

Mouse (Murine) ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

1. In conclusion, MiR29a regulates endothelial cell ADAM12 upregulation in ischemia and this is impaired in hyperglycemia.

2. It was concluded that TNF-alpha (show TNF Antibodies)-induced changes in extracellular matix components increased expression of ADAM12 among other changes that were temporally related with the onset of myocyte function.

3. ADAM12 and ADAM17 (show ADAM17 Antibodies) are essential molecules for the impairment of barrier function of retinal vasculature under hypoxia.

4. Augmentation of ADAM12 expression in vivo improved outcomes in Balb/c mice, whereas knockdown of ADAM12 made outcomes worse in C57Bl/6 mice. In vitro, ADAM12 expression modulates endothelial cell proliferation, survival, and angiogenesis.

5. The effect of insulin-like growth factor-I (show IGF1 Antibodies) on ADAM12 expression during the course of myogenesis is reported.

6. Nitric oxide synthase (show NOS Antibodies) deficiency has differential effects on ADAM12 expression in growing mouse brain.

7. Inhibition of Erbb2 (show ERBB2 Antibodies) suppressed the increase in metalloproteinase ADAM12 expression in skin tumors.

8. TGF-beta (show TGFB1 Antibodies) stimulation of renal cells results in a significant up-regulation of Adams 10, 17, 12, and 19

9. ADAM12 enhanced ephrin-A1 (show EFNA1 Antibodies) cleavage in response to transforming growth factor-betra1 in primary tumors.

10. The endogenous SnoN (show SKIL Antibodies) plays a role in regulating ADAM12 expression in response to TGFbeta1 (show TGFB1 Antibodies).

Human ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

1. Tetraspanin-8 (show TSPAN8 Antibodies) has a role in promoting hepatocellular carcinoma metastasis by increasing ADAM12m expression

2. A novel regulator, myoferlin (show MYOF Antibodies), of ADAM12 is discovered in HeLa cells and this protein increases ADAM12 expression level, stability, and its enzymatic activity, leading to the reduction of its substrate, E-cadherin (show CDH1 Antibodies), which plays important roles in the regulation of cell adhesion and tumor metastasis.

3. Our data support a role for ADAM12 in NHL (show RTEL1 Antibodies) cell proliferation, adhesion, and drug resistance, and it may pave the way for a novel therapeutic approach for CAM-DR in NHL (show RTEL1 Antibodies).

4. The rs3740199 polymorphism in the ADAM12 gene was associated with knee osteoarthritis genetic susceptibility.

5. These results indicate that ADAM12 actively supports the CSC phenotype in claudin-low breast cancer cells via modulation of the EGFR (show EGFR Antibodies) pathway.

6. We conclude that ADAM12 and MMP-14 (show MMP14 Antibodies) are associated with cavernous sinus invasion in pituitary adenomas, which qualifies these proteins in diagnosis and therapy.

7. ADAM12 expression is significantly upregulated in human masticatory mucosa during wound healing

8. Stromal expression patterns for both ADAM12 and CDCP1 (show CDCP1 Antibodies).

9. The first trimester maternal ADAM12-s levels were statistically significantly higher in the entire ART group, IVF (show SCN5A Antibodies) and ICSI groups, and normal cycle-frozen embryo transfer group when compared with those in the controls.

10. The level of ADAM12 was upregulated in tumor tissues of breast cancer compared to that of adjacent normal tissues. patients with higher level of ADAM12 exhibited shorter survival time compared to that of low level of ADAM12

Cow (Bovine) ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

1. These findings suggest ADAM12 is upregulated in muscles with more slow-oxidative myofibres, such as the LM, and is linked to type I myofibers in cattle.

2. The 5'- and 3'-regions of bovive ADAM12 have been analysed and compared to the human gene, and the promoter region has been cloned and sequenced.