anti-ATF6 Antibodies

Protein Summary

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.

Alternative names and synonyms associated with ATF6

• activating transcription factor 6 (ATF6) antibody
• uncharacterized LOC412432 (LOC412432) antibody
• activating transcription factor 6 S homeolog (atf6.S) antibody
• cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162) antibody
• activating transcription factor 6 (Atf6) antibody

• 9130025P16Rik antibody
• 9630036G24 antibody
• AA789574 antibody
• ATF-6-like antibody
• Atf6 antibody
• Show all synonym aliases
• ATF6A antibody
• Atf6alpha antibody
• ESTM49 antibody
• GB16435 antibody

Protein level used designations for ATF6

activating transcription factor 6 , cyclic AMP-dependent transcription factor ATF-6 alpha-like , cAMP-dependent transcription factor ATF-6 alpha , cyclic AMP-dependent transcription factor ATF-6 alpha