ERVK-16 Protein (AA 1-105) (His tag)
custom-made
ERVK-16
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- ERVK-16 (Endogenous Retrovirus Group K, Member 16 (ERVK-16))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-105
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ERVK-16 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant ERVK-16 Protein expressed in mammalian cells.
- Sequence
- MNPSEMQRKA PPRRRRHRNR APSSHKMNKM MMSEEQMKLP STNKAEPLTW AQLNKLTQLA TKCLENTKMT QTPESMLLAA LMIVSTVSAG VPNSSEETVT IENGP Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- ERVK-16 (Endogenous Retrovirus Group K, Member 16 (ERVK-16))
- Alternative Name
- ERVK-16
- Background
- Endogenous retrovirus group K member 16 Rec protein (HERV-K_10p14 provirus Rec protein),FUNCTION: Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript. Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery. This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity). {ECO:0000250}.
- Molecular Weight
- 11.8 kDa
- UniProt
- P61578
- AlphaFold
- P61578
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