Browse our anti-GIGYF2 (GIGYF2) Antibodies

Full name:: anti-GRB10 Interacting GYF Protein 2 Antibodies (GIGYF2)

On www.antibodies-online.com are 21 GRB10 Interacting GYF Protein 2 (GIGYF2) Antibodies from 10 different suppliers available. Additionally we are shipping GIGYF2 Proteins (3) and and many more products for this protein. A total of 28 GIGYF2 products are currently listed.

Synonyms:: 2610016F01Rik, A830080H02Rik, AI852361, AW259676, BC006835, fb57e02, GIGYF2, GYF2, im:6911549, mKIAA0642, PARK11, PERQ2, PERQ3, Tnrc15, wu:fb57e02, zgc:111944

list all antibodies	Gene Name	GeneID	UniProt
	GIGYF2	26058	Q6Y7W6
	GIGYF2	227331	Q6Y7W8
	GIGYF2
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anti-Human GIGYF2 Antibodies:

anti-Mouse (Murine) GIGYF2 Antibodies:

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anti-Dog (Canine) GIGYF2 Antibodies:

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Human GRB10 Interacting GYF Protein 2 (GIGYF2) interaction partners

genetic analyses of indel loci in ACE (show ACE Antibodies), DJ-1 (show PARK7 Antibodies), and GIGYF2 genes, was performed to explore the potential contribution of insertion (I)/deletion (D) polymorphisms (indels) to the risk of PD in a Chinese population.
Full-length GIGYF2 coimmunoprecipitates with AGO2 (show EIF2C2 Antibodies) in human cells, and upon tethering to a reporter mRNA, GIGYF2 exhibits strong, dose-dependent silencing activity, involving both mRNA destabilization and translational repression.
required, this finding may shed light on the GIGYF2-associated mechanisms that lead to PD and suggests insulin (show INS Antibodies) dysregulation as a disease-specific mechanism for both PD and cognitive dysfunction.
Results suggest that the N56S and N457T of GIGYF2 are risk factors for Parkinson's disease in Caucasians, but not in Asians
GIGYF2 and the zinc finger protein 598 (ZNF598) are identifie (show EIF4E Antibodies)d as components of the 4EHP complex.
Our result indicated that SCNA, LRRK2, UCHL1 (show UCHL1 Antibodies), HtrA2 (show HTRA2 Antibodies) and GIGYF2 genes' mutations might not be a main reason for Chinese Autosomal dorminant Parkinson's disease
within the Chinese population, the c.297T>C p.Ala99Ala polymorphism of the GIGYF2 gene may be associated with an increased risk of developing Parkinson disease.
These data, together with those recently reported by other groups, suggest that GIGYF2 is unlikely to be the PARK11 gene.
No clearly pathogenic mutations are identified in GIGYF2 and ATP13A2 (show ATP13A2 Antibodies) in Brazilian patients with early-onset Parkinson's disease.
The results of this study did not support a role for GIGYF2 in the genetic etiology of Belgian Parkinson disease.

Mouse (Murine) GRB10 Interacting GYF Protein 2 (GIGYF2) interaction partners

Negative regulation of Grb10 (show GRB10 Antibodies) Interacting GIGYF2 protein on IGF-1 (show IGF1 Antibodies) receptor signaling pathway caused diabetic mice cognitive impairment.
Disruption of the eukaryotic translation initiation factor 4E (show EIF4E Antibodies) - Gigyf2 complex leads to increased translation and perinatal lethality in mice.
Primary cultured embryo fibroblasts from Gigyf2 null mice exhibit decreased IGF1 (show IGF1 Antibodies) signaling.
identification of proteins linked to insulin (show INS Antibodies)-like growth factor (IGF-I (show IGF1 Antibodies)) receptors by the Grb10 (show GRB10 Antibodies) adapter and modulate IGF-I (show IGF1 Antibodies) signaling

GIGYF2 Antigen Profile

Antigen Summary

The protein encoded by this gene interacts with GRB10 and may be involved in the regulation of tyrosine kinase receptor signaling. This gene contains CAG repeats, and the encoded protein contains stretches glutamine and glutamic acid residues. Defects in this gene are a cause of Parkinson disease type 11 (PARK11). Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative names and synonyms associated with GIGYF2

GRB10 interacting GYF protein 2 (GIGYF2) antibody
GRB10 interacting GYF protein 2 (Gigyf2) antibody
GRB10 interacting GYF protein 2 (gigyf2) antibody
GRB10 interacting GYF protein 2 S homeolog (gigyf2.S) antibody

2610016F01Rik antibody
A830080H02Rik antibody
AI852361 antibody
AW259676 antibody
BC006835 antibody
fb57e02 antibody
GIGYF2 antibody
GYF2 antibody
im:6911549 antibody
mKIAA0642 antibody
PARK11 antibody
PERQ2 antibody
PERQ3 antibody
Tnrc15 antibody
wu:fb57e02 antibody
zgc:111944 antibody

Protein level used designations for GIGYF2

trinucleotide repeat containing 15 , GRB10 interacting GYF protein 2 , PERQ amino acid-rich with GYF domain-containing protein 2 , PERQ amino acid rich, with GYF domain 3 , Parkinson disease (autosomal recessive, early onset) 11 , trinucleotide repeat-containing gene 15 protein , GRB10-interacting GYF protein 2

GENE ID	SPECIES
424743	Gallus gallus
506913	Bos taurus
612838	Canis lupus familiaris
713675	Macaca mulatta
100021597	Monodelphis domestica
100064814	Equus caballus
100401755	Callithrix jacchus
100439308	Pongo abelii
100547124	Meleagris gallopavo
26058	Homo sapiens
227331	Mus musculus
561830	Danio rerio
495698	Xenopus laevis

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