GIGYF2 antibody (N-Term)

Catalog No. ABIN2789871

The Rabbit Polyclonal anti-GIGYF2 antibody (ABIN2789871) specifically detects GIGYF2 in WB. The antibody is reactive with Human, Mouse, Dog, Guinea Pig, Horse, Rat, Rabbit and Cow samples.

Quick Overview for GIGYF2 antibody (N-Term) (ABIN2789871)

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Reactivity: Human, Mouse, Dog, Guinea Pig, Horse, Rat, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIGYF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GIGYF2 Antibody

Binding Specificity: N-Term

Purpose: GIGYF2 Antibody - N-terminal region

Sequence: DDPGRPNFEE GGPTSVGRKH EFIRSESENW RIFREEQNGE DEDGGWRLAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GIGYF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human GIGYF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64542-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GIGYF2

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Alternative Name: GIGYF2

Background:

Background Information: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.

Gene Name: GRB10 interacting GYF protein 2

Alternative Symbols: GYF2, PERQ2, PERQ3, PARK11, TNRC15

Protein Name: PERQ amino acid-rich with GYF domain-containing protein 2

Molecular Weight: 150kDa

Gene ID: 26058

NCBI Accession: NP_001096616

UniProt: Q6Y7W6

Pathways: Feeding Behaviour, SARS-CoV-2 Protein Interactome