FGF2 Proteins
(Fibroblast Growth Factor 2 (Basic) (FGF2))
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].
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Latest Publications for our FGF2 Proteins
: "Basic fibroblast growth factor accelerates myelin debris clearance through activating autophagy to facilitate early peripheral nerve regeneration." in: Journal of cellular and molecular medicine, (2021) (PubMed).: "A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism." in: Cell reports, Vol. 26, Issue 11, pp. 2984-2997.e4, (2020) (PubMed).
: "ColXV Aggravates Adipocyte Apoptosis by Facilitating Abnormal Extracellular Matrix Remodeling in Mice." in: International journal of molecular sciences, Vol. 21, Issue 3, (2020) (PubMed).
: "Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination." in: Neuron, Vol. 102, Issue 3, pp. 587-601.e7, (2019) (PubMed).
: "Heparan Sulfate Microarray Reveals That Heparan Sulfate-Protein Binding Exhibits Different Ligand Requirements." in: Journal of the American Chemical Society, Vol. 139, Issue 28, pp. 9534-9543, (2018) (PubMed).
: "PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs." in: Nature communications, Vol. 8, Issue 1, pp. 672, (2018) (PubMed).
: "Lower Senescence of Adipose-Derived Stem Cells than Donor-Matched Bone Marrow Stem Cells for Surgical Ventricular Restoration." in: Stem cells and development, Vol. 27, Issue 9, pp. 612-623, (2018) (PubMed).
: "CD34 expression modulates tube-forming capacity and barrier properties of peripheral blood-derived endothelial colony-forming cells (ECFCs)." in: Angiogenesis, (2016) (PubMed).
: "Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds." in: Cell research, Vol. 26, Issue 1, pp. 34-45, (2016) (PubMed).
: "Defining minimum essential factors to derive highly pure human endothelial cells from iPS/ES cells in an animal substance-free system." in: Scientific reports, Vol. 5, pp. 9718, (2016) (PubMed).
Aliases for FGF2 Proteins
fibroblast growth factor 2 (FGF2) Proteinsfibroblast growth factor 2 (Fgf2) Proteins
fibroblast growth factor 2 (basic) (fgf2) Proteins
fibroblast growth factor 2 (fgf2) Proteins
BFGF Proteins
bFGF Proteins
FGF-2 Proteins
Fgf-2 Proteins
FGFB Proteins
Fgfb Proteins
HBGF-2 Proteins
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- FGFBP2 Proteins
- FGFR1 Proteins
- FGFR1OP Proteins
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- FGFRL1 Proteins
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