FGFR1b antibody (Ectodomain, Pro23)
The Mouse Monoclonal anti-FGFR1b antibody (Clone M17A3) (ABIN2961626) specifically detects FGFR1b in IP, IHC and WB.
The antibody is reactive with Human samples.
Catalog No. ABIN2961626
$1,296.53
Plus shipping costs $50.00
250 μg
Shipping to:
United States
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Quick Overview for FGFR1b antibody (Ectodomain, Pro23) (ABIN2961626)
Target
FGFR1b
(Fibroblast Growth Factor Receptor 1 beta (FGFR1b))
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Clone
M17A3
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Binding Specificity
- Ectodomain, Pro23
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Specificity
- Reacts with human Fibroblast Growth Factor Receptor 1 beta (FGFR1β). Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2-terminus of Ig loop II.
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Purification
- Purified (protein G)
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Immunogen
- Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.
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Isotype
- IgG2b
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(1 μg/mL) -
Restrictions
- For Research Use only
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Buffer
- PBS, pH 7.4.
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Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
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Storage
- -20 °C/-80 °C
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Storage Comment
- Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
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Expiry Date
- 12 months
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- FGFR1b (Fibroblast Growth Factor Receptor 1 beta (FGFR1b))
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Background
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Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
FGFR-1 Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1 Fms-like tyrosine kinase 2, FLT-2 N-sam Proto-oncogene c-Fgr CD_antigen : CD331 CEK FLG HH2 OGD KAL2 HBGFR HRTFDS Gene name : FGFR1 -
Gene ID
- 2260
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UniProt
- P11362
Target
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