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GRP78 Proteins

(Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010].

25 results

HSPA5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3009776
 
HSPA5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723102
 
HSPA5 Origin: Rat Host: Escherichia coli (E. coli) Recombinant SDS, WB
Catalog No. ABIN6123352
 
HSPA5 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7584759
 
HSPA5 Origin: Pig Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1472489
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Functional Studies (Func)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Pig
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Hi-5 Cells
    • Yeast
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 19-654
    • AA 20-650
    • AA 20-655
    • AA 261-470
    • AA 1-262
    • AA 25-293
    • AA 260-469
    • full length
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • Abbexa
    • CUSABIO
    • OriGene
    • Signalway

Latest Publications for our GRP78 Proteins

Chen, Zhang, Yu, Chong, Yoshioka, Ge: "Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction." in: Cell death and differentiation, Vol. 21, Issue 5, pp. 797-810, (2014) (PubMed).

Čiplys, Aučynaitė, Slibinskas: "Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae." in: Microbial cell factories, Vol. 13, pp. 22, (2014) (PubMed).

Kosakowska-Cholody, Lin, Srideshikan, Scheffer, Tarasova, Acharya: "HKH40A downregulates GRP78/BiP expression in cancer cells." in: Cell death & disease, Vol. 5, pp. e1240, (2014) (PubMed).

Bruchmann, Roller, Walther, Schäfer, Lehmusvaara, Visakorpi, Klocker, Cato, Maddalo: "Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis." in: BMC cancer, Vol. 13, pp. 96, (2013) (PubMed).

Ding, Li, Wu, Yang, Luo, Xie, Druey, Zajac, Hsu, Mountz: "IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 4, pp. 1614-24, (2013) (PubMed).

Maddalo, Neeb, Jehle, Schmitz, Muhle-Goll, Shatkina, Walther, Bruchmann, Gopal, Wenzel, Ulrich, Cato: "A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death." in: PLoS ONE, Vol. 7, Issue 10, pp. e45690, (2012) (PubMed).

Taylor, Gercel-Taylor, Parker: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." in: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).

Zwang, Hoffert, Pisitkun, Moeller, Fenton, Knepper: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).

Ting, Lee: "Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 4, pp. 275-86, (1988) (PubMed).

Aliases for GRP78 Proteins

78 kDa glucose-regulated protein (CpipJ_CPIJ003550) Proteins
heat shock protein family A (Hsp70) member 5 (HSPA5) Proteins
78 kDa glucose-regulated protein (grp78) Proteins
BiP/GRP78 (LOC100533358) Proteins
glucose-regulated protein 78 (BiP/grp78) Proteins
glucose-regulated protein 78 (Tc00.1047053506585.40) Proteins
glucose-regulated protein 78 (Tb11.02.5450) Proteins
glucose-regulated protein 78 (Tb11.02.5500) Proteins
putative glucose-regulated protein 78 (LMJF_28_1200) Proteins
Hsp70 family ATPase KAR2 (KAR2) Proteins
78 kDa glucose-regulated protein (LOC100135840) Proteins
heat shock protein family A (Hsp70) member 5 S homeolog (hspa5.S) Proteins
heat shock 70 kDa protein 5a (hspa5) Proteins
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5) Proteins
heat shock protein family A (Hsp70) member 5 (Hspa5) Proteins
heat shock protein 5 (Hspa5) Proteins
heat shock protein family A member 5 (Hspa5) Proteins
heat shock protein 5 (hspa5) Proteins
AL022860 Proteins
AU019543 Proteins
baffled Proteins
BiP Proteins
BIP Proteins
Bip Proteins
cb865 Proteins
D2Wsu17e Proteins
D2Wsu141e Proteins
fb60h09 Proteins
fi36d04 Proteins
GRP-78 Proteins
GRP78 Proteins
grp78 Proteins
Grp78 Proteins
Hsce70 Proteins
hspa5a Proteins
mBiP Proteins
MIF2 Proteins
SEZ-7 Proteins
Sez7 Proteins
wu:fb60h09 Proteins
wu:fi36d04 Proteins
zgc:55994 Proteins
zgc:77606 Proteins
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