(Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012].
Crane, Han, Ahn, Oehlke, Kivett, Fedoroff, Butowski, Chang, Clarke, Berger, McDermott, Prados, Parsa: "Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 1, pp. 205-14, (2013) (PubMed).
Aliases for GRP94 Proteins
heat shock protein 90kDa beta (Grp94), member 1 (hsp90b1) Proteins heat shock protein Hsp90 family protein (grp94) Proteins 94 kD glucose-regulated protein (grp94) Proteins heat shock protein 90 beta family member 1 (HSP90B1) Proteins heat shock protein 90, beta (Grp94), member 1 (Hsp90b1) Proteins heat shock protein 90, beta (grp94), member 1 (hsp90b1) Proteins heat shock protein 90 beta family member 1 (Hsp90b1) Proteins heat shock protein 90kDa beta family member 1 L homeolog (hsp90b1.L) Proteins heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1) Proteins DDBDRAFT_0206450 Proteins DDBDRAFT_0215015 Proteins DDB_0206450 Proteins DDB_0215015 Proteins ecgp Proteins ECGP Proteins endoplasmin Proteins ERp99 Proteins fb61d09 Proteins gp96 Proteins GP96 Proteins Gp96 Proteins grp94 Proteins GRP94 Proteins Grp94 Proteins HSP90B1 Proteins hsp108 Proteins ppk98 Proteins TA-3 Proteins Targ2 Proteins Tra-1 Proteins tra-1 Proteins tra1 Proteins TRA1 Proteins Tra1 Proteins wu:fb61d09 Proteins wu:fq25g01 Proteins