Histone Cluster 2, H4 (HIST2H4) (Middle Region) Peptide
Quick Overview for Histone Cluster 2, H4 (HIST2H4) (Middle Region) Peptide (ABIN978011)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hist2h4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HIST2H4 (Histone Cluster 2, H4 (HIST2H4))
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Background
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Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H4, X04652
Protein Size: 103 -
Molecular Weight
- 11 kDa
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Gene ID
- 97122
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NCBI Accession
- NM_033596, NP_291074
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UniProt
- P62806
Target
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