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Histone Cluster 2, H4 (HIST2H4) (Middle Region) Peptide

HIST2H4 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN978011

Quick Overview for Histone Cluster 2, H4 (HIST2H4) (Middle Region) Peptide (ABIN978011)

Target

HIST2H4 (Histone Cluster 2, H4 (HIST2H4))

Origin

Human, Mouse

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-Hist2h4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HIST2H4 (Histone Cluster 2, H4 (HIST2H4))

    Background

    Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Alias Symbols: H4, X04652

    Protein Size: 103

    Molecular Weight

    11 kDa

    Gene ID

    97122

    NCBI Accession

    NM_033596, NP_291074

    UniProt

    P62806
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