anti-SMPD3 Antibodies

Protein Summary

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Acts as a regulator of postnatal development and participates in bone and dentin mineralization. Overexpression enhances cell death, suggesting that it may be involved in apoptosis control. May be involved in IL-1-beta-induced JNK activation in hepatocytes. May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF- kappa-B activation under inflammatory conditions.

Alternative names and synonyms associated with SMPD3

• sphingomyelin phosphodiesterase 3 (SMPD3) antibody
• sphingomyelin phosphodiesterase 3, neutral (Smpd3) antibody
• sphingomyelin phosphodiesterase 3 (Smpd3) antibody

• 4631433G07Rik antibody
• AI427456 antibody
• AW537966 antibody
• cca1 antibody
• fro antibody
• Show all synonym aliases
• NSMASE2 antibody

Protein level used designations for SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) , nSMase-2 , neutral sphingomyelinase 2 , neutral sphingomyelinase II , sphingomyelin phosphodiesterase 3 , confluent 3Y1 cell-associated 1 , confluent 3Y1 cell-associated protein 1 , nSMase2 , neutral sphingomyelin phosphodiesterase 3