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IL1RN Proteins

(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

55 results

IL1RN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >97 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2830838
$678.48
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
IL1RN Origin: Rat Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6123863
$703.66
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
 
IL1RN Origin: Mouse Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
Catalog No. ABIN6239774
$800.00
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
IL1RN Origin: Human Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
Catalog No. ABIN6239773
$800.00
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
IL1RN Origin: Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3010131
$888.46
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
 
IL1RN Origin: Horse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2830529
$1,124.64
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
IL1RN Origin: Cow Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7584817
$1,280.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7584818
$1,282.60
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Dog Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1645844
$2,800.60
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Tursiops truncatus Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1650932
$2,805.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Cynomolgus Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1623905
$2,805.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Pig Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1622097
$2,805.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Rabbit Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1473177
$2,805.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Horse Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1462238
$2,805.00
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
 
IL1RN Origin: Pig Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN6305810
$3,167.66
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
    • Activity Assay (AcA)
    • Affinity Measurement (AM)
    • Functional Studies (Func)
    • Immunoassay (IA)
    • Immunoprecipitation (IP)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Cell Culture (CC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Biochemical Assay (BCA)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Dog
    • Pig
    • Cow
    • Horse
    • Rabbit
    • Rat
    • Monkey
    • Cynomolgus
    • Rhesus Monkey
    • Tursiops truncatus
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Bacteria
    • HEK-293T Cells
    • Wheat germ
  • Binding Specificity
    • AA 26-177
    • AA 27-178
    • AA 18-332
    • AA 24-174
    • AA 26-176
    • Transcript Variant 3
    • AA 1-159
    • AA 25-178
    • AA 8-159
    • Transcript Variant 1
    • Transcript Variant 4
  • Conjugate
    • His tag
    • Un-conjugated
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
    • Fc Tag
    • GST tag
    • mFc Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene
    • Abbexa
    • Cloud-Clone
    • ProteoGenix

Latest Publications for our IL1RN Proteins

Wang, Zhen, Fan, Qin, Han, Zhou, Wang, An: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hunt, Xu, Finkelstein, Fan, Carroll, Cheng, Eisenman, Demontis: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." in: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).

Hedl, Abraham: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." in: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).

Hedl, Abraham: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).

OShaughnessy, Choudhary, Harper: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).

Eisenberg, Brewer, Verderber, Heimdal, Brandhuber, Thompson: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).

Carter, Deibel, Dunn, Tomich, Laborde, Slightom, Berger, Bienkowski, Sun, McEwan: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." in: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).

Aliases for IL1RN Proteins

interleukin 1 receptor antagonist (IL1RN) Proteins
interleukin 1 receptor antagonist (Il1rn) Proteins
interleukin 1 receptor antagonist-like (IL1RNL) Proteins
DIRA Proteins
F630041P17Rik Proteins
ICIL-1RA Proteins
IL-1ra Proteins
IL-1RA Proteins
IL-1ra3 Proteins
IL-1RN Proteins
IL1F3 Proteins
IL1RA Proteins
IL1RN Proteins
IRAP Proteins
IRAP1 Proteins
MVCD4 Proteins
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