Interleukin 17a Proteins
(Interleukin 17A (IL17A))
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008].
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IL17A
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
MALS verified
IL17A
Origin: Human
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
IL17A
Origin: Dog
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
IL17A
Origin: Mouse
Host: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, ELISA, WB, MS
IL17A
Origin: Rat
Host: Yeast
Recombinant
> 90 %
ELISA
Latest Publications for our Interleukin 17a Proteins
: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." in: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).: "An HIV-1 replication pathway utilizing reverse transcription products that fail to integrate." in: Journal of virology, Vol. 87, Issue 23, pp. 12701-20, (2013) (PubMed).
: "Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death." in: Diabetes, Vol. 60, Issue 8, pp. 2112-9, (2011) (PubMed).
: "Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ..." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22299-307, (2010) (PubMed).
: "IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4531-7, (2010) (PubMed).
Aliases for Interleukin 17a Proteins
interleukin 17A (IL17A) Proteinsinterleukin 17A (Il17a) Proteins
ChIL-17 Proteins
Ctla-8 Proteins
CTLA-8 Proteins
CTLA8 Proteins
Ctla8 Proteins
IL-17 Proteins
IL-17A Proteins
IL-17F Proteins
IL17 Proteins
Il17 Proteins
IL17A Proteins
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